MedKoo Cat#: 577031 | Name: MDL-74366 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDL-74366 HCl is the tertiary amine analogue of MDL-74270 -- a cardioselective alpha-tocopherol analogue.

Chemical Structure

MDL-74366 HCl
MDL-74366 HCl
CAS#128008-98-0

Theoretical Analysis

MedKoo Cat#: 577031

Name: MDL-74366 HCl

CAS#: 128008-98-0

Chemical Formula: C19H30ClNO3

Exact Mass: 355.1914

Molecular Weight: 355.90

Elemental Analysis: C, 64.12; H, 8.50; Cl, 9.96; N, 3.94; O, 13.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
MDL74366 hydrochloride; MDL74366 HCl; MDL 74366 HCl; MDL-74366 HCl
IUPAC/Chemical Name
2H-1-Benzopyran-6-ol, 2-(2-(dimethylamino)ethyl)-3,4-dihydro-2,5,7,8-tetramethyl-, acetate (ester), hydrochloride
InChi Key
JMEHNOZNAWODKF-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H29NO3.ClH/c1-12-13(2)18-16(14(3)17(12)22-15(4)21)8-9-19(5,23-18)10-11-20(6)7;/h8-11H2,1-7H3;1H
SMILES Code
Cl.CN(C)CCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 355.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Petty MA, Dow J, Grisar JM, De Jong W. Effect of a cardioselective alpha-tocopherol analogue on reperfusion injury in rats induced by myocardial ischaemia. Eur J Pharmacol. 1991 Jan 17;192(3):383-8. doi: 10.1016/0014-2999(91)90229-j. PMID: 2055237. 2. Abadie C, Ben Baouali A, Maupoil V, Rochette L. An alpha-tocopherol analogue with antioxidant activity improves myocardial function during ischemia reperfusion in isolated working rat hearts. Free Radic Biol Med. 1993 Aug;15(2):209-15. doi: 10.1016/0891-5849(93)90061-x. PMID: 8375694. 3. Walker MK, Vergely C, Lecour S, Abadie C, Maupoil V, Rochette L. Vitamin E analogues reduce the incidence of ventricular fibrillations and scavenge free radicals. Fundam Clin Pharmacol. 1998;12(2):164-72. doi: 10.1111/j.1472-8206.1998.tb00937.x. PMID: 9565770.