F-15741 | CAS#unknown | NaV1.5 mediated inhibitor

MedKoo Cat#: 464911 | Name: F-15741

Description:

WARNING: This product is for research use only, not for human or veterinary use.

F-15741 is a selective, potent inhibitor of the late current mediated by the cardiac isoform of the sodium channel (NaV1.5).

Chemical Structure

F-15741

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464911

Name: F-15741

CAS#: unknown

Chemical Formula: C20H25NO2S2

Exact Mass: 375.1327

Molecular Weight: 375.55

Elemental Analysis: C, 63.97; H, 6.71; N, 3.73; O, 8.52; S, 17.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

F-15741; F15741; F 15741;

IUPAC/Chemical Name

2-(((S)-3-(((R)-3,4-dihydro-2H-benzo[b][1,4]oxathiepin-3-yl)amino)-2-methylpropyl)thio)-6-methylphenol

InChi Key

KHMJPCBCJWSRNL-GOEBONIOSA-N

InChi Code

InChI=1S/C20H25NO2S2/c1-14(12-24-19-9-5-6-15(2)20(19)22)10-21-16-11-23-17-7-3-4-8-18(17)25-13-16/h3-9,14,16,21-22H,10-13H2,1-2H3/t14-,16+/m0/s1

SMILES Code

C[C@H](CSC1=CC=CC(C)=C1O)CN[C@@H]2COC3=CC=CC=C3SC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 375.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Le Grand B, Pignier C, Létienne R, Colpaert F, Cuisiat F, Rolland F, Mas A, Borras M, Vacher B. Na+ currents in cardioprotection: better to be late. J Med Chem. 2009 Jul 23;52(14):4149-60. doi: 10.1021/jm900296e. PMID: 19514733.