Nicocortonide Free Base | CAS# 65415-41-0 (free base) | synthetic glucocorticoid corticosteroid

MedKoo Cat#: 414367 | Name: Nicocortonide Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nicocortonide Free Base is a synthetic glucocorticoid corticosteroid which was never marketed.

Chemical Structure

Nicocortonide Free Base

CAS#65415-41-0 (free base)

Theoretical Analysis

MedKoo Cat#: 414367

Name: Nicocortonide Free Base

CAS#: 65415-41-0 (free base)

Chemical Formula: C31H37NO7

Exact Mass: 535.2570

Molecular Weight: 535.64

Elemental Analysis: C, 69.51; H, 6.96; N, 2.62; O, 20.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

28202-60-0 (acetate) 65415-41-0 (free base)

Synonym

Nicocortonide Free Base; Nicocortonida; Nicocortonidum

IUPAC/Chemical Name

2-((1R,4aR,4bR,10aR,10bS,11S,12aS)-11-hydroxy-10a,12a-dimethyl-8-oxo-3-((Z)-prop-1-en-1-yl)-5,6,8,9,10,10a,10b,11,12,12a-decahydro-1,4a-ethanophenanthro[1,2-d][1,3]dioxin-1(4bH)-yl)-2-oxoethyl isonicotinate

InChi Key

LZHLAFIPUJPCBN-ZTOAAZPKSA-N

InChi Code

InChI=1S/C31H37NO7/c1-4-5-25-38-30-12-13-31(39-25,24(35)18-37-27(36)19-9-14-32-15-10-19)29(30,3)17-23(34)26-22(30)7-6-20-16-21(33)8-11-28(20,26)2/h4-5,9-10,14-16,22-23,25-26,34H,6-8,11-13,17-18H2,1-3H3/b5-4-/t22-,23+,25?,26-,28+,29+,30-,31+/m1/s1

SMILES Code

C/C=C\C1O[C@@]23CC[C@](C(COC(c4ccncc4)=O)=O)([C@]2(C[C@@H]([C@H]5[C@H]3CCC6=CC(CC[C@]56C)=O)O)C)O1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 535.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Saarni H, Jalkanen M, Hopsu-Havu VK. Effect of five anti-inflammatory steroids on collagen and glycoaminoglycan synthessis in vitro. Br J Dermatol. 1980 Aug;103(2):167-73. doi: 10.1111/j.1365-2133.1980.tb06586.x. PMID: 7426413.