MedKoo Cat#: 576953 | Name: Zomepirac free acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zomepirac is a prostaglandin synthetase inhibitor. Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions.

Chemical Structure

Zomepirac free acid
Zomepirac free acid
CAS#33369-31-2 (free acid)

Theoretical Analysis

MedKoo Cat#: 576953

Name: Zomepirac free acid

CAS#: 33369-31-2 (free acid)

Chemical Formula: C15H14ClNO3

Exact Mass: 291.0662

Molecular Weight: 291.73

Elemental Analysis: C, 61.76; H, 4.84; Cl, 12.15; N, 4.80; O, 16.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
33369-31-2 (free acid) 64092-48-4 (sodium) 64092-49-5 (sodium hydrate)
Synonym
McN-2783-21-98; Zomepirac free acid
IUPAC/Chemical Name
1H-Pyrrole-2-acetic acid, 5-(4-chlorobenzoyl)-1,4-dimethyl-, sodium salt, dihydrate
InChi Key
ZXVNMYWKKDOREA-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14ClNO3/c1-9-7-12(8-13(18)19)17(2)14(9)15(20)10-3-5-11(16)6-4-10/h3-7H,8H2,1-2H3,(H,18,19)
SMILES Code
O=C(O)CC1=CC(C)=C(C(C2=CC=C(Cl)C=C2)=O)N1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. McEvoy GK. Evaluation of zomepirac sodium. Am J Hosp Pharm. 1981 Sep;38(9):1293-301. PMID: 7025615. 2. Muschek LD, Grindel JM. Review of the pharmacokinetics and metabolism of zomepirac in man and animals. J Clin Pharmacol. 1980 Apr;20(4):223-9. doi: 10.1002/j.1552-4604.1980.tb01702.x. PMID: 6769977. 3. McLeod DC. Zomepirac (Zomax, McNeil Pharmaceutical). Drug Intell Clin Pharm. 1981 Jul-Aug;15(7-8):522-30. doi: 10.1177/1060028081015007-802. PMID: 7018870.