MedKoo Cat#: 414324 | Name: Mebutizide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mebutizide is a diuretic.

Chemical Structure

Mebutizide
Mebutizide
CAS#3568-00-1

Theoretical Analysis

MedKoo Cat#: 414324

Name: Mebutizide

CAS#: 3568-00-1

Chemical Formula: C13H20ClN3O4S2

Exact Mass: 381.0584

Molecular Weight: 381.89

Elemental Analysis: C, 40.89; H, 5.28; Cl, 9.28; N, 11.00; O, 16.76; S, 16.79

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Mebutizide; Mebuthiazide; Neoniagar
IUPAC/Chemical Name
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(1,2-dimethylbutyl)-3,4-dihydro-, 1,1-dioxide
InChi Key
KJLLKLRVCJAFRY-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H20ClN3O4S2/c1-4-7(2)8(3)13-16-10-5-9(14)11(22(15,18)19)6-12(10)23(20,21)17-13/h5-8,13,16-17H,4H2,1-3H3,(H2,15,18,19)
SMILES Code
O=S(C1=C(Cl)C=C(C2=C1)NC(C(C)C(C)CC)NS2(=O)=O)(N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Mebutizide is a diuretic.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 381.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: BELLUSCHI A, TALLONE G. ACTIVITE DIURETIQUE DU MEBUTIZIDE-TRIAMTERENE. ETUDE CLINIQUE [DIURETIC ACTIVITY OF MEBUTIZIDE-TRIAMTERENE. CLINICAL STUDY]. Acta Cardiol. 1965;20:238-45. French. PMID: 14314170. 2: MAGGI CA, BARBI G, TALLONE G. SUR UNE NOUVELLE ASSOCIATION DIUR'ETIQUE: M'EBUTIZIDE AVEC TRIAMT'ER'ENE. RAPPORT CLINIQUE [ON A NEW DIURETIC COMBINATION: MEBUTIZIDE WITH TRIAMTERENE. CLINICAL REPORT]. Brux Med. 1965 Feb 28;45:231-8. French. PMID: 14294779. 3: Nicaise J, Ghirardi P. Etude clinique croisée en double aveugle de l'action hypotensive de la reserpine seule et associée à un diurétique (mebutizide [Double-blind cross-over study of the hypotensive action of reserpine alone and associated with a diuretic (mebutizide)]. Brux Med. 1973 Nov;53(11):683-8. French. PMID: 4769204.