MedKoo Cat#: 130014 | Name: SST0116CL1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SST0116CL1 is a heat shock protein 90 inhibitor that inhibits tumor growth by binding to the ATP pocket of Hsp90, interfering with the function of the chaperone of Hsp90. SST0116CL1 has been shown to have the potential to be a candidate for use in cancer therapy.

Chemical Structure

SST0116CL1
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130014

Name: SST0116CL1

CAS#: N/A

Chemical Formula: C22H31ClN4O6

Exact Mass: 482.1932

Molecular Weight: 482.96

Elemental Analysis: C, 54.71; H, 6.47; Cl, 7.34; N, 11.60; O, 19.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SST0116CL1
IUPAC/Chemical Name
5-(2,4-Dihydroxy-5-isopropyl-phenyl)-N-ethyl-4-(3-morpholinopropanoylamino)isoxazole-3-carboxamide
InChi Key
IJBIOWMKHRRFCS-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H30N4O6.ClH/c1-4-23-22(30)20-19(24-18(29)5-6-26-7-9-31-10-8-26)21(32-25-20)15-11-14(13(2)3)16(27)12-17(15)28;/h11-13,27-28H,4-10H2,1-3H3,(H,23,30)(H,24,29);1H
SMILES Code
O=C(C1=NOC(C2=CC(C(C)C)=C(O)C=C2O)=C1NC(CCN3CCOCC3)=O)NCC.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 482.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Vesci L, Milazzo FM, Carollo V, Pace S, Giannini G. Preclinical antitumor activity of SST0116CL1: a novel heat shock protein 90 inhibitor. Int J Oncol. 2014 Oct;45(4):1421-9. doi: 10.3892/ijo.2014.2575. Epub 2014 Aug 1. PMID: 25096516; PMCID: PMC4151799.