NBI-921352 is a potent, highly selective Nav1.6 sodium channel inhibitor being developed to treat pediatric patients with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) and other potential indications, including adult focal epilepsy.
MedKoo Cat#: 414292
Name: NBI-921352
CAS#: 2154406-04-7 (free base)
Chemical Formula: C22H25FN4O2S2
Exact Mass: 460.1403
Molecular Weight: 460.59
Elemental Analysis: C, 57.37; H, 5.47; F, 4.12; N, 12.16; O, 6.95; S, 13.92
The following data is based on the product molecular weight 460.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
