MedKoo Cat#: 464755 | Name: BVQ1814

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BVQ1814 is a novel highly effective fluorescent probe, targeting phosphodiesterase 10A with a highly potent affinity and a >1000-fold subfamily selectivity by gaining insights into the three-dimensional structural information of the active site of the catalytic pocket.

Chemical Structure

BVQ1814
BVQ1814
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464755

Name: BVQ1814

CAS#: unknown

Chemical Formula: C33H34N6O3

Exact Mass: 562.2692

Molecular Weight: 562.67

Elemental Analysis: C, 70.44; H, 6.09; N, 14.94; O, 8.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BVQ1814; BVQ 1814; BVQ-1814;
IUPAC/Chemical Name
(E)-8-(2-(5-methyl-1-(3-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazol-2-yl)vinyl)-5-nitroquinoline
InChi Key
ZYVYUDCTUKALJG-SDNWHVSQSA-N
InChi Code
InChI=1S/C33H34N6O3/c1-24-9-12-31-29(22-24)35-32(14-11-25-10-13-30(39(40)41)28-8-4-15-34-33(25)28)38(31)26-6-3-7-27(23-26)42-21-5-16-37-19-17-36(2)18-20-37/h3-4,6-15,22-23H,5,16-21H2,1-2H3/b14-11+
SMILES Code
O=[N+](C1=C2C=CC=NC2=C(/C=C/C3=NC4=CC(C)=CC=C4N3C5=CC=CC(OCCCN6CCN(C)CC6)=C5)C=C1)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 562.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gao Y, Huang J, Zhou Q, Liu R, Zhang S, Zhang C, Huang YY, Li Z, Huang L, Wu D, Wu Y, Xiao L, Guo L, Luo HB. Discovery of Highly Specific Catalytic-Site- Targeting Fluorescent Probes for Detecting Lysosomal PDE10A in Living Cells. ACS Chem Biol. 2021 May 21;16(5):857-863. doi: 10.1021/acschembio.1c00018. Epub 2021 May 6. PMID: 33955736.