MedKoo Cat#: 414242 | Name: Khl 8430

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Khl 8430 is a potent and specific inhibitor of calmodulin activity.

Chemical Structure

Khl 8430
Khl 8430
CAS#132324-32-4

Theoretical Analysis

MedKoo Cat#: 414242

Name: Khl 8430

CAS#: 132324-32-4

Chemical Formula: C25H29NO2

Exact Mass: 375.2198

Molecular Weight: 375.51

Elemental Analysis: C, 79.96; H, 7.78; N, 3.73; O, 8.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Khl 8430; Khl 8430; Khl 8430
IUPAC/Chemical Name
N-(1-(3,4-dimethoxyphenyl)ethyl)-3,3-diphenylpropan-1-amine
InChi Key
UWKOIXGMEPYUTC-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H29NO2/c1-19(22-14-15-24(27-2)25(18-22)28-3)26-17-16-23(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-15,18-19,23,26H,16-17H2,1-3H3
SMILES Code
COc1c(OC)cc(C(NCCC(c2ccccc2)c3ccccc3)C)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 375.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Orosz F, Telegdi M, Liliom K, Solti M, Korbonits D, Ovádi J. Dissimilar mechanisms of action of anticalmodulin drugs: quantitative analysis. Mol Pharmacol. 1990 Dec;38(6):910-6. PMID: 2147457. 2: Marko R, Kelemen K. A dual membrane stabilizing and calcium blocking effect of KHL-8430 (Chinoin), a fendilin analog on the heart. Acta Physiol Hung. 1990;75 Suppl:203-4. PMID: 2371863.