MedKoo Cat#: 464745 | Name: Azide-A-DSBSO
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azide-A-DSBSO is a novel Enrichable and MS-Cleavable Cross-linker to Define Protein-Protein Interactions by Mass Spectrometry. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

Azide-A-DSBSO
Azide-A-DSBSO
CAS#1704097-02-8

Theoretical Analysis

MedKoo Cat#: 464745

Name: Azide-A-DSBSO

CAS#: 1704097-02-8

Chemical Formula: C24H33N5O12S2

Exact Mass: 647.1567

Molecular Weight: 647.67

Elemental Analysis: C, 44.51; H, 5.14; N, 10.81; O, 29.64; S, 9.90

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
AUN-00648; AUN 00648; AUN 00648; azide-A-DSBSO;
IUPAC/Chemical Name
bis(2,5-dioxopyrrolidin-1-yl) 3,3'-((2-(3-azidopropyl)-2-methyl-1,3-dioxane-5,5-diyl)bis(methylenesulfinyl))dipropionate
InChi Key
AKLJWXIVLPURNY-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H33N5O12S2/c1-23(9-2-10-26-27-25)38-13-24(14-39-23,15-42(36)11-7-21(34)40-28-17(30)3-4-18(28)31)16-43(37)12-8-22(35)41-29-19(32)5-6-20(29)33/h2-16H2,1H3
SMILES Code
CC1(CCCN=[N+]=[N-])OCC(CS(CCC(ON2C(CCC2=O)=O)=O)=O)(CS(CCC(ON3C(CCC3=O)=O)=O)=O)CO1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 647.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Matzinger M, Kandioller W, Doppler P, Heiss EH, Mechtler K. Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides. J Proteome Res. 2020 May 1;19(5):2071-2079. doi: 10.1021/acs.jproteome.0c00003. Epub 2020 Apr 16. PMID: 32250121; PMCID: PMC7199212. 2: Burke AM, Kandur W, Novitsky EJ, Kaake RM, Yu C, Kao A, Vellucci D, Huang L, Rychnovsky SD. Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein-protein interactions by mass spectrometry. Org Biomol Chem. 2015 May 7;13(17):5030-7. doi: 10.1039/c5ob00488h. PMID: 25823605; PMCID: PMC4420144.