Exp3312 | CAS# 114798-35-5 | Antagonizes angiotensin receptor AII-1 site

MedKoo Cat#: 414179 | Name: Exp3312

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Exp3312 antagonizes angiotensin receptor AII-1 site.

Chemical Structure

Exp3312

CAS#114798-35-5

Theoretical Analysis

MedKoo Cat#: 414179

Name: Exp3312

CAS#: 114798-35-5

Chemical Formula: C21H19ClN6O

Exact Mass: 406.1309

Molecular Weight: 406.87

Elemental Analysis: C, 61.99; H, 4.71; Cl, 8.71; N, 20.66; O, 3.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Exp3312; Exp-3312; Exp 3312

IUPAC/Chemical Name

1H-Imidazole-5-carboxaldehyde, 4-chloro-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-

InChi Key

IMVDZFOSXJSXFP-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H19ClN6O/c1-2-5-19-23-20(22)18(13-29)28(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21-24-26-27-25-21/h3-4,6-11,13H,2,5,12H2,1H3,(H,24,25,26,27)

SMILES Code

O=CC1=C(Cl)N=C(CCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 406.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wong YN, Wong PC. Pharmacological and pharmacokinetic evaluation of EXP3312, an orally-active non-peptide angiotensin II-receptor antagonist. J Pharm Pharmacol. 1996 May;48(5):492-7. doi: 10.1111/j.2042-7158.1996.tb05960.x. PMID: 8799873. 2: DeNoble VJ, DeNoble KF, Spencer KR, Chiu AT, Wong PC, Timmermans PB. Non- peptide angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor: effect on a renin-induced deficit of a passive avoidance response in rats. Brain Res. 1991 Oct 11;561(2):230-5. doi: 10.1016/0006-8993(91)91599-v. PMID: 1802340.