Synonym
Halicin; SU-3327; SU 3327; SU3327
IUPAC/Chemical Name
5-[(5-Ntro-1,3-thiazol-2-yl)sulfanyl]-1,3,4-thiadiazol-2-amine
InChi Key
NQQBNZBOOHHVQP-UHFFFAOYSA-N
InChi Code
InChI=1S/C5H3N5O2S3/c6-3-8-9-5(14-3)15-4-7-1-2(13-4)10(11)12/h1H,(H2,6,8)
SMILES Code
NC1=NN=C(SC2=NC=C([N+]([O-])=O)S2)S1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
261.29
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kutlu Z, Celik M, Bilen A, Halıcı Z, Yıldırım S, Karabulut S, Karakaya S, Bostanlık DF, Aydın P. Effects of umbelliferone isolated from the Ferulago pauciradiata Boiss. & Heldr. Plant on cecal ligation and puncture-induced sepsis model in rats. Biomed Pharmacother. 2020 May 4;127:110206. doi: 10.1016/j.biopha.2020.110206. Epub ahead of print. PMID: 32407990.
2: Polat G, Ugan RA, Cadirci E, Halici Z. Sepsis and Septic Shock: Current Treatment Strategies and New Approaches. Eurasian J Med. 2017 Feb;49(1):53-58. doi: 10.5152/eurasianjmed.2017.17062. PMID: 28416934; PMCID: PMC5389495.
3: Emet M, Ozcan H, Ozel L, Yayla M, Halici Z, Hacimuftuoglu A. A Review of Melatonin, Its Receptors and Drugs. Eurasian J Med. 2016 Jun;48(2):135-41. doi: 10.5152/eurasianjmed.2015.0267. PMID: 27551178; PMCID: PMC4970552.
4: Seyrek M, Halici Z, Yildiz O, Ulusoy HB. Interaction between dexmedetomidine and α-adrenergic receptors: emphasis on vascular actions. J Cardiothorac Vasc Anesth. 2011 Oct;25(5):856-62. doi: 10.1053/j.jvca.2011.06.006. Epub 2011 Sep 8. PMID: 21862350.
5: Suleyman H, Albayrak A, Bilici M, Cadirci E, Halici Z. Different mechanisms in formation and prevention of indomethacin-induced gastric ulcers. Inflammation. 2010 Aug;33(4):224-34. doi: 10.1007/s10753-009-9176-5. PMID: 20084447.
6: Suleyman H, Cadirci E, Albayrak A, Halici Z. Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. Curr Med Chem. 2008;15(3):278-83. doi: 10.2174/092986708783497247. PMID: 18333314.
