MedKoo Cat#: 576859 | Name: Mandelamide
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mandelamide is a biochemical.

Chemical Structure

Mandelamide
Mandelamide
CAS#4410-31-5

Theoretical Analysis

MedKoo Cat#: 576859

Name: Mandelamide

CAS#: 4410-31-5

Chemical Formula: C8H9NO2

Exact Mass: 151.0633

Molecular Weight: 151.17

Elemental Analysis: C, 63.56; H, 6.00; N, 9.27; O, 21.17

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 400.00 2 Weeks
25g USD 650.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Mandelamide
IUPAC/Chemical Name
Benzeneacetamide, alpha-hydroxy-
InChi Key
MAGPZHKLEZXLNU-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H9NO2/c9-8(11)7(10)6-4-2-1-3-5-6/h1-5,7,10H,(H2,9,11)
SMILES Code
NC(=O)C(O)c1ccccc1
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Mandelamide is a biochemical.
In vitro activity:
This study investigated the inhibitory effects of compounds extracted from P. persica flowers (PPF) on adipogenesis in 3T3-L1 murine preadipocytes using adipogenic differentiation assays. Among them, mandelamide (4) exhibited the maximum inhibitory activity with an IC50 of 36.04 ± 1.82 μM. Additionally, mandelamide downregulated the expression of key adipogenic markers, such as extracellular signal-regulated kinase, c-Jun-N-terminal kinase, P38, CCAAT/enhancer-binding protein α, CCAAT/enhancer-binding protein β, peroxisome proliferator activated receptor γ, and glucocorticoid receptor. Reference: Bioorg Med Chem Lett. 2021 Oct 1;49:128326. https://pubmed.ncbi.nlm.nih.gov/34403725/
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 151.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
Lee D, Kim JY, Qi Y, Park S, Lee HL, Yamabe N, Kim H, Jang DS, Kang KS. Phytochemicals from the flowers of Prunus persica (L.) Batsch: Anti-adipogenic effect of mandelamide on 3T3-L1 preadipocytes. Bioorg Med Chem Lett. 2021 Oct 1;49:128326. doi: 10.1016/j.bmcl.2021.128326. Epub 2021 Aug 14. PMID: 34403725.
In vitro protocol:
Lee D, Kim JY, Qi Y, Park S, Lee HL, Yamabe N, Kim H, Jang DS, Kang KS. Phytochemicals from the flowers of Prunus persica (L.) Batsch: Anti-adipogenic effect of mandelamide on 3T3-L1 preadipocytes. Bioorg Med Chem Lett. 2021 Oct 1;49:128326. doi: 10.1016/j.bmcl.2021.128326. Epub 2021 Aug 14. PMID: 34403725.
In vivo protocol:
TBD