MedKoo Cat#: 111532 | Name: Norendimide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Norendimide, which produces excitation, is the endo-isomer of noreximide, a sedative.

Chemical Structure

Norendimide
Norendimide
CAS#6265-30-1

Theoretical Analysis

MedKoo Cat#: 111532

Name: Norendimide

CAS#: 6265-30-1

Chemical Formula: C9H9NO2

Exact Mass: 163.0633

Molecular Weight: 163.18

Elemental Analysis: C, 66.25; H, 5.56; N, 8.58; O, 19.61

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
5g USD 950.00 2 Weeks
10g USD 1,650.00 2 Weeks
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Related CAS #
3647-74-3 (exo-isomer) 6265-30-1 (endo-isomer)
Synonym
Nadic imide, NSC 31977, NSC31977, NSC-319733, NSC 53245, NSC-53245, NSC53245
IUPAC/Chemical Name
(3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
InChi Key
GPIUUMROPXDNRH-UMRXKNAASA-N
InChi Code
InChI=1S/C9H9NO2/c11-8-6-4-1-2-5(3-4)7(6)9(12)10-8/h1-2,4-7H,3H2,(H,10,11,12)/t4-,5+,6-,7+
SMILES Code
O=C1NC([C@@H]2[C@H]3C[C@@H]([C@H]12)C=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Norendimide, which produces excitation, is the endo-isomer of noreximide, a sedative.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 163.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Tan HS, Pan PW. High-performance liquid chromatographic separation of noreximide and norendimide in bulk material, tablets and animal feed. J Chromatogr. 1987 Aug 28;404(1):233-41. doi: 10.1016/s0021-9673(01)86853-9. PMID: 3680435. 2: Koch HP, Bykadi G, Ledesma B, Ritschel WA. Pharmacokinetics of noreximide in the beagle dog. Methods Find Exp Clin Pharmacol. 1982;4(8):587-90. PMID: 7169847. 3: Koch HP, Pischek G, Czejka M, Ritschel WA. Pharmacokinetic evaluation of norendimide in rats. Methods Find Exp Clin Pharmacol. 1982;4(8):581-5. PMID: 7169846. 4: Koch HP, Pischek G, Holzbecher M, Ritschel WA. Pharmacokinetic evaluation of noreximide in rats. Biopharm Drug Dispos. 1981 Jul-Sep;2(3):245-53. doi: 10.1002/bdd.2510020305. PMID: 7295881.