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MedKoo Cat#: 414075 | Name: Medazepam HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Medazepam HCl is a benzodiazepine derivative used in the treatment of anxiety. It has sedative, muscle relaxant, and anticonvulsant properties. One of its metabolites is DIAZEPAM and one of its excretion products is OXAZEPAM.

Chemical Structure

Medazepam HCl
Medazepam HCl
CAS#2898-11-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 414075

Name: Medazepam HCl

CAS#: 2898-11-5 (HCl)

Chemical Formula: C16H16Cl2N2

Exact Mass:

Molecular Weight: 307.22

Elemental Analysis: C, 62.55; H, 5.25; Cl, 23.08; N, 9.12

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
2898-11-5 (HCl) 2898-12-6 (free base)
Synonym
Medazepam HCl; Medazepam hydrochloride; CCRIS1916; CCRIS-1916; CCRIS 1916
IUPAC/Chemical Name
1H-1,4-Benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl, monohydrochloride
InChi Key
XBWAZCLHZCFCGK-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H15ClN2.ClH/c1-19-10-9-18-16(12-5-3-2-4-6-12)14-11-13(17)7-8-15(14)19;/h2-8,11H,9-10H2,1H3;1H
SMILES Code
CN1CCN=C(C2=CC=CC=C2)C3=CC(Cl)=CC=C31.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 307.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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A new method for the simultaneous determination of 1,4-benzodiazepines and amfepramone as adulterants in phytotherapeutic formulations by voltammetry. Forensic Sci Int. 2010 Oct 10;202(1-3):75-81. doi: 10.1016/j.forsciint.2010.04.030. Epub 2010 May 15. PubMed PMID: 20472377. 16: Millefiori S, Alparone A. Electronic properties of neuroleptics: ionization energies of benzodiazepines. J Mol Model. 2011 Feb;17(2):281-7. doi: 10.1007/s00894-010-0723-7. Epub 2010 May 6. PubMed PMID: 20446010. 17: Papoutsis II, Athanaselis SA, Nikolaou PD, Pistos CM, Spiliopoulou CA, Maravelias CP. Development and validation of an EI-GC-MS method for the determination of benzodiazepine drugs and their metabolites in blood: applications in clinical and forensic toxicology. J Pharm Biomed Anal. 2010 Aug 1;52(4):609-14. doi: 10.1016/j.jpba.2010.01.027. Epub 2010 Feb 1. PubMed PMID: 20172681. 18: Vrzal R, Kubesova K, Pavek P, Dvorak Z. 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