MedKoo Cat#: 559301 | Name: Cloperidone HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cloperidone showed central nervous system depressant activity at doses ranging from 0.06% to 1.9% of its acute LD50 in mice and rats. The dose-response curves of central depressant activity of MA1337 were flat.

Chemical Structure

Cloperidone HCl
Cloperidone HCl
CAS#525-26-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 559301

Name: Cloperidone HCl

CAS#: 525-26-8 (HCl)

Chemical Formula: C21H24Cl2N4O2

Exact Mass: 0.0000

Molecular Weight: 435.35

Elemental Analysis: C, 57.94; H, 5.56; Cl, 16.29; N, 12.87; O, 7.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Cloperidone HCl; Ma 1337; Ma-1337; Ma1337; NSC 198100; NSC-198100; NSC198100;
IUPAC/Chemical Name
2,4(1H,3H)-Quinazolinedione, 3-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride
InChi Key
QUGOVTRSGWYKSQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H23ClN4O2.ClH/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28;/h1-3,5-8,15H,4,9-14H2,(H,23,28);1H
SMILES Code
O=C(N1CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)NC4=C(C=CC=C4)C1=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 435.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
FUJIMORI H, COBB DP. CENTRAL NERVOUS SYSTEM DEPRESSANT ACTIVITY OF MA1337, 3-(3-(4-M-CHLOROPHENYL-1-PIPERAZYL)PROPYL)-2,4(1H,3H)QUINAZOLINEDIONE HYDROCHLORIDE. J Pharmacol Exp Ther. 1965 May;148:151-7. PMID: 14302151.