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MedKoo Cat#: 414059 | Name: ER 42859

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ER 42859 is anew semi-synthetic oral erythromycin derivative with antimicrobial activity

Chemical Structure

ER 42859
ER 42859
CAS#107749-17-7

Theoretical Analysis

MedKoo Cat#: 414059

Name: ER 42859

CAS#: 107749-17-7

Chemical Formula: C43H81N3O14

Exact Mass: 863.5719

Molecular Weight: 864.13

Elemental Analysis: C, 59.77; H, 9.45; N, 4.86; O, 25.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ER 42859; ER-42859; ER42859
IUPAC/Chemical Name
(Z)-6-((4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12-((2-(dimethylamino)ethoxy)methoxy)-14-ethyl-7,13-dihydroxy-4-((5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(methoxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
InChi Key
OYWJWZVRBXELPW-SWYSEXKRSA-N
InChi Code
InChI=1S/C43H81N3O14/c1-17-31-43(10,51)38(55-23-54-19-18-45(11)12)26(4)33(44-53-16)24(2)21-41(8,50)37(60-40-34(47)30(46(13)14)20-25(3)56-40)27(5)35(28(6)39(49)58-31)59-32-22-42(9,52-15)36(48)29(7)57-32/h24-32,34-38,40,47-48,50-51H,17-23H2,1-16H3/b44-33-
SMILES Code
CCC1OC(C(C(C(C(C(O)(CC(/C(C(C(C1(O)C)OCOCCN(C)C)C)=N/OC)C)C)OC2OC(CC(N(C)C)C2O)C)C)OC3CC(OC)(C(C(O3)C)O)C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 864.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wilson JM, Hannan PC, Shillingford C, Knowles DJ. Biological properties of ER 42859, a novel erythromycin derivative. J Antibiot (Tokyo). 1989 Mar;42(3):454-62. doi: 10.7164/antibiotics.42.454. PMID: 2708138. 2: Hung LF, Brumbaugh AE, Bhatia G, Marion PL, Hung PP, Norbeck DW, Plattner JJ, Robinson WS. Effects of purine nucleoside analogues with a cyclobutane ring and erythromycin A oxime derivatives on duck hepatitis B virus replication in vivo and in cell culture and HIV-1 in cell culture. J Med Virol. 1991 Nov;35(3):180-6. doi: 10.1002/jmv.1890350307. PMID: 1804929.