IS-741 potassium | CAS# 141284-74-4 | Biochemical

MedKoo Cat#: 576774 | Name: IS-741 potassium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IS-741 potassium is a phospholipase A2 inhibitor.

Chemical Structure

IS-741 potassium

CAS#141284-74-4

Theoretical Analysis

MedKoo Cat#: 576774

Name: IS-741 potassium

CAS#: 141284-74-4

Chemical Formula: C15H19F3KN3O3S

Exact Mass: 417.0736

Molecular Weight: 417.49

Elemental Analysis: C, 43.15; H, 4.59; F, 13.65; K, 9.37; N, 10.07; O, 11.50; S, 7.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

IS-741-monok salt; IS-741 potassium; IS 741 potassium; IS741 potassium

IUPAC/Chemical Name

Cyclohexanecarboxamide, N-(2-((ethylsulfonyl)amino)-5-(trifluoromethyl)-3-pyridinyl)-, potassium salt (1:1)

InChi Key

RAZLFMFISMFZBG-UHFFFAOYSA-M

InChi Code

InChI=1S/C15H20F3N3O3S.K/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10;/h8-10H,2-7H2,1H3,(H2,19,20,21,22);/q;+1/p-1

SMILES Code

[K+].CCS(=O)(=O)[N-]c1ncc(cc1NC(=O)C2CCCCC2)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 417.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Garcia-Garcia HM, Serruys PW. Phospholipase A2 inhibitors. Curr Opin Lipidol. 2009 Aug;20(4):327-32. doi: 10.1097/MOL.0b013e32832dd4c7. Review. PubMed PMID: 19550325. 2: Farooqui AA, Ong WY, Horrocks LA. Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacol Rev. 2006 Sep;58(3):591-620. Review. PubMed PMID: 16968951. 3: Meyer MC, Rastogi P, Beckett CS, McHowat J. Phospholipase A2 inhibitors as potential anti-inflammatory agents. Curr Pharm Des. 2005;11(10):1301-12. Review. PubMed PMID: 15853686.