RM-581-Fluo | CAS#unknown | RM-581 N-dimethyl analogue

MedKoo Cat#: 464612 | Name: RM-581-Fluo

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RM-581-Fluo is a N-dimethyl analogue of RM-581. the RM-581-Fluo EC50 value (7.1 μM) was found to be close to the RM-581 value (EC50 = 3.7 μM), with only a slight (1.9-fold) loss of activity. Considering their similar molecular structure, physicochemical and ADME, as well as cytotoxic activity, RM-581-Fluo seems to be a valuable probe of RM-581 that was further tested for its fluorescent properties.

Chemical Structure

RM-581-Fluo

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464612

Name: RM-581-Fluo

CAS#: unknown

Chemical Formula: C43H59N5O4

Exact Mass: 709.4567

Molecular Weight: 709.98

Elemental Analysis: C, 72.75; H, 8.38; N, 9.86; O, 9.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RM-581-Fluo; RM-581 Fluo; RM581-Fluo; RM581 Fluo; RM 581-Fluo; RM 581 Fluo;

IUPAC/Chemical Name

(6-(dimethylamino)quinolin-2-yl)((S)-2-(4-((2S,3S,5S,8R,9S,10S,13S,14S,17R)-17-ethynyl-17-hydroxy-3-methoxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-2-yl)piperazine-1-carbonyl)pyrrolidin-1-yl)methanone

InChi Key

HMTSIQUWWNUTRF-IRHBSPJGSA-N

InChi Code

InChI=1S/C43H59N5O4/c1-7-43(51)19-17-33-31-13-11-29-26-38(52-6)37(27-41(29,2)32(31)16-18-42(33,43)3)46-21-23-47(24-22-46)40(50)36-9-8-20-48(36)39(49)35-14-10-28-25-30(45(4)5)12-15-34(28)44-35/h1,10,12,14-15,25,29,31-33,36-38,51H,8-9,11,13,16-24,26-27H2,2-6H3/t29-,31+,32-,33-,36-,37-,38-,41-,42-,43-/m0/s1

SMILES Code

O=C(N1CCN([C@H]2C[C@]3(C)[C@@]4([H])CC[C@]5(C)[C@](O)(C#C)CC[C@@]5([H])[C@]4([H])CC[C@@]3([H])C[C@@H]2OC)CC1)[C@H]6N(C(C7=NC8=CC=C(N(C)C)C=C8C=C7)=O)CCC6

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 709.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.