MCB-3837 sodium | CAS# 856676-92-1 | Biochemical

MedKoo Cat#: 576928 | Name: MCB-3837 sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MCB-3837 sodium is an oxazolidinone-quinolone hybrid molecule with antibacterial activity.

Chemical Structure

MCB-3837 sodium

CAS#856676-92-1

Theoretical Analysis

MedKoo Cat#: 576928

Name: MCB-3837 sodium

CAS#: 856676-92-1

Chemical Formula: C31H32F2N4NaO11P

Exact Mass: 728.1671

Molecular Weight: 728.57

Elemental Analysis: C, 51.11; H, 4.43; F, 5.22; N, 7.69; Na, 3.16; O, 24.16; P, 4.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MCB-3837 sodium; MCB 3837 sodium; MCB3837 sodium

IUPAC/Chemical Name

3-Quinolinecarboxylic acid, 7-(4-((4-((5S)-5-((acetylamino)methyl)-2-oxo-3-oxazolidinyl)-2-fluorophenoxy)methyl)-4-(phosphonooxy)-1-piperidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, sodium salt

InChi Key

YJXYMDNRYHCPHB-BDQAORGHSA-M

InChi Code

InChI=1S/C31H33F2N4O11P.Na/c1-17(38)34-13-20-14-37(30(42)47-20)19-4-5-27(24(33)10-19)46-16-31(48-49(43,44)45)6-8-35(9-7-31)26-12-25-21(11-23(26)32)28(39)22(29(40)41)15-36(25)18-2-3-18;/h4-5,10-12,15,18,20H,2-3,6-9,13-14,16H2,1H3,(H,34,38)(H,40,41)(H2,43,44,45);/q;+1/p-1/t20-;/m0./s1

SMILES Code

[Na+].CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(OCC3(CCN(CC3)c4cc5N(C=C(C(=O)O)C(=O)c5cc4F)C6CC6)OP(=O)(O)[O-])c(F)c2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 728.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Rashid MU, Dalhoff A, Bäckström T, Björkhem-Bergman L, Panagiotidis G, Weintraub A, Nord CE. Ecological impact of MCB3837 on the normal human microbiota. Int J Antimicrob Agents. 2014 Aug;44(2):125-30. doi: 10.1016/j.ijantimicag.2014.03.016. Epub 2014 May 23. PMID: 24931053. 2. Dalhoff A, Rashid MU, Kapsner T, Panagiotidis G, Weintraub A, Nord CE. Analysis of effects of MCB3681, the antibacterially active substance of prodrug MCB3837, on human resident microflora as proof of principle. Clin Microbiol Infect. 2015 Aug;21(8):767.e1-4. doi: 10.1016/j.cmi.2015.05.025. Epub 2015 Jun 3. PMID: 26047854.