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MedKoo Cat#: 413946 | Name: Tiprenolol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tiprenolol is a beta adrenergic receptor antagonist.

Chemical Structure

Tiprenolol
CAS#13379-86-7 (free base)

Theoretical Analysis

MedKoo Cat#: 413946

Name: Tiprenolol

CAS#: 13379-86-7 (free base)

Chemical Formula: C13H21NO2S

Exact Mass: 255.1293

Molecular Weight: 255.38

Elemental Analysis: C, 61.14; H, 8.29; N, 5.48; O, 12.53; S, 12.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
39832-43-4 (HCl) 13379-86-7 (free base)
Synonym
Tiprenolol; DU21445; DU-21445; DU 21445
IUPAC/Chemical Name
2-Propanol, 1-((1-methylethyl)amino)-3-(2-(methylthio)phenoxy)-
InChi Key
CSUNLSYSEQIDMO-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H21NO2S/c1-10(2)14-8-11(15)9-16-12-6-4-5-7-13(12)17-3/h4-7,10-11,14-15H,8-9H2,1-3H3
SMILES Code
OC(COC1=CC=CC=C1SC)CNC(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 255.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Allen JD, Shanks RG. Effects of tiprenolol, practolol and propranolol on experimental ventricular tachyarrhythmias. Br J Pharmacol. 1974 Jun;51(2):179-85. doi: 10.1111/j.1476-5381.1974.tb09645.x. PMID: 4155971; PMCID: PMC1776753. 2: Iizuka H, Nakagawa Y, Matsubara I, Imai S, Yanagita T. [Drug effects on blood pressure and heart rate in unanesthetized animals. (1). Effects of beta-blocking agents (author's transl)]. Nihon Yakurigaku Zasshi. 1977 May;73(4):401-9. Japanese. doi: 10.1254/fpj.73.401. PMID: 20392. 3: Roelandt J, Schamroth L, Hugenholtz PG. Effects of new beta-blocking agent (DL-tiprenolol) on conduction within normal and anomalous atrioventricular pathways in Wolff-Parkinson-White syndrome. Br Heart J. 1972 Dec;34(12):1272-82. doi: 10.1136/hrt.34.12.1272. PMID: 4405234; PMCID: PMC487069. 4: Kesteloot H, Sluyts R, Floor-Wieringa A, van Strik R. Pharmacological studies with tiprenolol and propranolol in man. Eur J Pharmacol. 1973 Mar;21(3):257-63. doi: 10.1016/0014-2999(73)90124-6. PMID: 4145318. 5: Yan V, Sloman G. Double blind cross-over study of the inotropic influence of Tiprenolol (DU21445) and propranolol in patients with ischaemic heart disease. Aust N Z J Med. 1973 Oct;3(5):467-73. doi: 10.1111/j.1445-5994.1973.tb03124.x. PMID: 4149632.