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MedKoo Cat#: 576616 | Name: IMD-1622

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IMD-1622 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor.

Chemical Structure

IMD-1622
IMD-1622
CAS#848601-97-8

Theoretical Analysis

MedKoo Cat#: 576616

Name: IMD-1622

CAS#: 848601-97-8

Chemical Formula: C26H20O7

Exact Mass: 444.1209

Molecular Weight: 444.44

Elemental Analysis: C, 70.27; H, 4.54; O, 25.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
IMD-1622; IMD 1622; IMD1622
IUPAC/Chemical Name
2,4-Thiazolidinedione, 3-((3,4-dichlorophenyl)methyl)-5-((3,4,5-trihydroxyphenyl)methylene)-
InChi Key
LOGYYEXKVXHOIW-NSIKDUERSA-N
InChi Code
InChI=1S/C17H11Cl2NO5S/c18-10-2-1-8(3-11(10)19)7-20-16(24)14(26-17(20)25)6-9-4-12(21)15(23)13(22)5-9/h1-6,21-23H,7H2/b14-6-
SMILES Code
Oc1cc(\C=C\2/SC(=O)N(Cc3ccc(Cl)c(Cl)c3)C2=O)cc(O)c1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 444.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Watanabe R, Nakajima T, Ogawa M, Suzuki J, Muto S, Itai A, Hirata Y, Nagai R, Isobe M. Effects of pharmacological suppression of plasminogen activator inhibitor-1 in myocardial remodeling after ischemia reperfusion injury. Int Heart J. 2011;52(6):388-92. doi: 10.1536/ihj.52.388. PMID: 22188714. 2. Ogawa M, Suzuki J, Yamaguchi Y, Muto S, Itai A, Hirata Y, Isobe M, Nagai R. The effects of pharmacologic plasminogen activator inhibitor-1 inhibition in acute and chronic rejection in murine cardiac allografts. Transplantation. 2011 Jan 15;91(1):21-6. doi: 10.1097/tp.0b013e3181fd3c0f. PMID: 21452408. 3. Suzuki J, Ogawa M, Muto S, Yamaguchi Y, Itai A, Isobe M. The effects of pharmacological PAI-1 inhibition on thrombus formation and neointima formation after arterial injury. Expert Opin Ther Targets. 2008 Jul;12(7):783-94. doi: 10.1517/14728222.12.7.783. PMID: 18554148. 4. Suzuki J, Ogawa M, Muto S, Itai A, Isobe M. A specific inhibitor of plasminogen activator inhibitor-1 suppresses rat autoimmune myocarditis. Expert Opin Ther Targets. 2008 Nov;12(11):1313-20. doi: 10.1517/14728222.12.11.1313. PMID: 18851689.