ICR-364 dihydrochloride | CAS# 38915-24-1 | Biochemical

MedKoo Cat#: 576557 | Name: ICR-364 dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICR-364 dihydrochloride is a mutagen that induces frameshift mutations via DNA intercalation.

Chemical Structure

ICR-364 dihydrochloride

CAS#38915-24-1

Theoretical Analysis

MedKoo Cat#: 576557

Name: ICR-364 dihydrochloride

CAS#: 38915-24-1

Chemical Formula: C17H20Cl4N4O

Exact Mass: 436.0391

Molecular Weight: 438.17

Elemental Analysis: C, 46.60; H, 4.60; Cl, 32.36; N, 12.79; O, 3.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICR 364 dihydrochloride; ICR-364 dihydrochloride; ICR364 dihydrochloride

IUPAC/Chemical Name

1,2-Ethanediamine, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-, dihydrochloride

InChi Key

IWSFAWVCAZYOIF-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H18Cl2N4O.2ClH/c1-24-15-5-4-13-17(23-15)16(21-9-8-20-7-6-18)12-3-2-11(19)10-14(12)22-13;;/h2-5,10,20H,6-9H2,1H3,(H,21,22);2*1H

SMILES Code

Cl.Cl.COc1ccc2nc3cc(Cl)ccc3c(NCCNCCCl)c2n1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 438.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Oeschger NS, Hartman PE. ICR-induced frameshift mutations in the histidine operon of Salmonella. J Bacteriol. 1970 Feb;101(2):490-504. doi: 10.1128/JB.101.2.490-504.1970. PMID: 4905310; PMCID: PMC284933.