MedKoo Cat#: 413792 | Name: Dioxethedrin HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dioxethedrin HCl is the ephedrine derivative. It is the beta-adrenergic agonist. As a bronchodilator and sympathomimetic agent is was used in antitussive syrup Bexol.

Chemical Structure

Dioxethedrin HCl
Dioxethedrin HCl
CAS#22930-85-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 413792

Name: Dioxethedrin HCl

CAS#: 22930-85-4 (HCl)

Chemical Formula: C11H18ClNO3

Exact Mass: 0.0000

Molecular Weight: 247.72

Elemental Analysis: C, 53.34; H, 7.32; Cl, 14.31; N, 5.65; O, 19.38

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Synonym
Dioxethedrin HCl; Dioxethedrin hydrochloride; Dioxethedrine Hydrochloride;
IUPAC/Chemical Name
4-(2-(Ethylamino)-1-hydroxypropyl)pyrocatechol hydrochloride
InChi Key
FUJODHUUJJFEIR-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H17NO3.ClH/c1-3-12-7(2)11(15)8-4-5-9(13)10(14)6-8;/h4-7,11-15H,3H2,1-2H3;1H
SMILES Code
OC1=CC=C(C(O)C(NCC)C)C=C1O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Dioxethedrin HCl is the beta-adrenergic agonist.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 247.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: PORTMANN M, DELAGE R. ASSOCIATION ANTITUSSIVE DIOXETHEDRINE-CODEINE- PROMETHAZINE [THE ANTITUSSIVE COMBINATION DIOXETHEDRINE-CODEINE-PROMETHAZINE]. Rev Laryngol Otol Rhinol (Bord). 1964 Nov-Dec;85:1073-81. French. PMID: 14266725.