MedKoo Cat#: 413783 | Name: Dioscoretine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dioscoretine is a hypoglycemic agent and thus is useful for therapeutic treatment of conditions such as diabetes mellitus isolated from Dioscorea dumetorum.

Chemical Structure

Dioscoretine
Dioscoretine
CAS#128637-87-6

Theoretical Analysis

MedKoo Cat#: 413783

Name: Dioscoretine

CAS#: 128637-87-6

Chemical Formula: C13H23NO3

Exact Mass: 241.1678

Molecular Weight: 241.33

Elemental Analysis: C, 64.70; H, 9.61; N, 5.80; O, 19.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Dioscoretine
IUPAC/Chemical Name
(3S)-4-((1R,4R)-5-hydroxy-2-methyl-2-azabicyclo[2.2.2]octan-5-yl)-3-methylbutanoic acid
InChi Key
YWVYEZNFPRWGMM-RUPPFBPSSA-N
InChi Code
InChI=1S/C13H23NO3/c1-9(5-12(15)16)6-13(17)7-11-4-3-10(13)8-14(11)2/h9-11,17H,3-8H2,1-2H3,(H,15,16)/t9-,10-,11-,13?/m1/s1
SMILES Code
C[C@@H](CC1(C[C@H]2CC[C@@H]1CN2C)O)CC(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 241.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Iwu MM, Okunji CO, Akah P, Tempesta MS, Corley D. Dioscoretine: the hypoglycemic principle of Dioscorea dumetorum. Planta Med. 1990 Feb;56(1):119-20. doi: 10.1055/s-2006-960901. PMID: 2356236. 2: Iwu MM, Okunji CO, Ohiaeri GO, Akah P, Corley D, Tempesta MS. Hypoglycaemic activity of dioscoretine from tubers of Dioscorea dumetorum in normal and alloxan diabetic rabbits. Planta Med. 1990 Jun;56(3):264-7. doi: 10.1055/s-2006-960952. PMID: 2392490.