MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 592158 | Name: Thenoyltrifluoroacetone
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.

Chemical Structure

Thenoyltrifluoroacetone
Thenoyltrifluoroacetone
CAS#326-91-0

Theoretical Analysis

MedKoo Cat#: 592158

Name: Thenoyltrifluoroacetone

CAS#: 326-91-0

Chemical Formula: C6H5F3O2S

Exact Mass: 221.9962

Molecular Weight: 221.18

Elemental Analysis: C, 43.25; H, 2.27; F, 25.65; O, 14.40; S, 14.43

Price and Availability

Size Price Availability Quantity
25g USD 270.00
100g USD 470.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Thenoyltrifluoroacetone; NSC 66544; NSC-66544; NSC66544
IUPAC/Chemical Name
1,3-Butanedione, 4,4,4-trifluoro-1-(2-thienyl)-
InChi Key
TXBBUSUXYMIVOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H5F3O2S/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2
SMILES Code
O=C(C1=CC=CS1)CC(C(F)(F)F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 221.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wu X, Gao H, Hou Y, Yu J, Sun W, Wang Y, Chen X, Feng Y, Xu QM, Chen X. Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways. Toxicol Appl Pharmacol. 2018 Jun 12;355:1-8. doi: 10.1016/j.taap.2018.06.007. [Epub ahead of print] PubMed PMID: 29906494. 2: Cary SK, Livshits M, Cross JN, Ferrier MG, Mocko V, Stein BW, Kozimor SA, Scott BL, Rack JJ. Advancing Understanding of the +4 Metal Extractant Thenoyltrifluoroacetonate (TTA(-)); Synthesis and Structure of M(IV)TTA(4) (M(IV) = Zr, Hf, Ce, Th, U, Np, Pu) and M(III)(TTA)(4)(-) (M(III) = Ce, Nd, Sm, Yb). Inorg Chem. 2018 Apr 2;57(7):3782-3797. doi: 10.1021/acs.inorgchem.7b03089. Epub 2018 Mar 21. PubMed PMID: 29561140. 3: Wang X, Yang Y, Du G, Chen N, Zhang A. Broadband UV Excited LaF₃:Eu(3+) Based Inorganic-Organic Mixed Hybrid Nanoparticles for Strong Luminescence. J Nanosci Nanotechnol. 2018 Mar 1;18(3):1876-1881. doi: 10.1166/jnn.2018.14214. PubMed PMID: 29448675. 4: Dokpikul N, Chaiyasith WC, Sananmuang R, Ampiah-Bonney RJ. Surfactant-assisted emulsification dispersive liquid-liquid microextraction using 2-thenoyltrifluoroacetone as a chelating agent coupled with electrothermal atomic absorption spectrometry for the speciation of chromium in water and rice samples. Food Chem. 2018 Apr 25;246:379-385. doi: 10.1016/j.foodchem.2017.11.050. Epub 2017 Nov 14. PubMed PMID: 29291862. 5: Li XY, Wu J, Luo D, Chen WX, Zhu GL, Zhang YX, Bi ZM, Feng BH. [Effect of high glucose-based peritoneal dialysis fluids on NLRP3-IL-1β in human peritoneal mesothelial cells]. Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Dec 18;49(6):954-960. Chinese. PubMed PMID: 29263464. 6: Hori E, Kikuchi C, Nagami C, Kajikuri J, Itoh T, Takeuchi M, Matsunaga T. Role of Glyceraldehyde-Derived AGEs and Mitochondria in Superoxide Production in Femoral Artery of OLETF Rat and Effects of Pravastatin. Biol Pharm Bull. 2017 Nov 1;40(11):1903-1908. doi: 10.1248/bpb.b17-00411. Epub 2017 Aug 22. PubMed PMID: 28835584. 7: Singh K, Boddula R, Vaidyanathan S. Versatile Luminescent Europium(III)-β-Diketonate-imidazo-bipyridyl Complexes Intended for White LEDs: A Detailed Photophysical and Theoretical Study. Inorg Chem. 2017 Aug 7;56(15):9376-9390. doi: 10.1021/acs.inorgchem.7b01565. Epub 2017 Jul 26. PubMed PMID: 28745502. 8: Tien YE, Huang WC, Kuo HY, Tai L, Uang YS, Chern WH, Huang JD. Pharmacokinetics of dinalbuphine sebacate and nalbuphine in human after intramuscular injection of dinalbuphine sebacate in an extended-release formulation. Biopharm Drug Dispos. 2017 Nov;38(8):494-497. doi: 10.1002/bdd.2088. Epub 2017 Sep 14. PubMed PMID: 28741675. 9: Teplova VV, Belosludtsev KN, Kruglov AG. Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett. 2017 Jun 5;275:108-117. doi: 10.1016/j.toxlet.2017.05.004. Epub 2017 May 4. PubMed PMID: 28478158. 10: Weng H, Xu XY, Yan B. Novel multi-component photofunctional nanohybrids for ratio-dependent oxygen sensing. J Colloid Interface Sci. 2017 Sep 15;502:8-15. doi: 10.1016/j.jcis.2017.04.081. Epub 2017 Apr 27. PubMed PMID: 28475939. 11: Ren X, Ren L, Wei Q, Shao H, Chen L, Liu N. Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. Cardiovasc Diabetol. 2017 Apr 20;16(1):52. doi: 10.1186/s12933-017-0531-9. PubMed PMID: 28427390; PubMed Central PMCID: PMC5397770. 12: Sun W, Wu X, Gao H, Yu J, Zhao W, Lu JJ, Wang J, Du G, Chen X. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. Free Radic Biol Med. 2017 Jul;108:433-444. doi: 10.1016/j.freeradbiomed.2017.04.010. Epub 2017 Apr 14. PubMed PMID: 28414098. 13: Restovic F, Espinoza-Corral R, Gómez I, Vicente-Carbajosa J, Jordana X. An active Mitochondrial Complex II Present in Mature Seeds Contains an Embryo-Specific Iron-Sulfur Subunit Regulated by ABA and bZIP53 and Is Involved in Germination and Seedling Establishment. Front Plant Sci. 2017 Feb 28;8:277. doi: 10.3389/fpls.2017.00277. eCollection 2017. PubMed PMID: 28293251; PubMed Central PMCID: PMC5329045. 14: Zhao W, Feng H, Sun W, Liu K, Lu JJ, Chen X. Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion. Redox Biol. 2017 Apr;11:524-534. doi: 10.1016/j.redox.2016.12.036. Epub 2017 Jan 5. PubMed PMID: 28088644; PubMed Central PMCID: PMC5237803. 15: Tamás L, Zelinová V. Mitochondrial complex II-derived superoxide is the primary source of mercury toxicity in barley root tip. J Plant Physiol. 2017 Feb;209:68-75. doi: 10.1016/j.jplph.2016.10.014. Epub 2016 Dec 5. PubMed PMID: 28013172. 16: Kazemi E, Haji Shabani AM, Dadfarnia S. Application of graphene oxide-silica composite reinforced hollow fibers as a novel device for pseudo-stir bar solid phase microextraction of sulfadiazine in different matrices prior to its spectrophotometric determination. Food Chem. 2017 Apr 15;221:783-789. doi: 10.1016/j.foodchem.2016.11.103. Epub 2016 Nov 22. PubMed PMID: 27979273. 17: Lin J, Feng C, He X, Wang W, Fang Y, Liu Z, Li J, Tang C, Huang Y. Europium (III) Organic Complexes in Porous Boron Nitride Microfibers: Efficient Hybrid Luminescent Material. Sci Rep. 2016 Sep 30;6:34576. doi: 10.1038/srep34576. PubMed PMID: 27687246; PubMed Central PMCID: PMC5043355. 18: Wang J, Li Z, Wang T, Yang D, Wang Y. Transparent Layer Derived from Layered Europium Hydroxide Sensitized with 2-Thenoyltrifluoroacetone. J Nanosci Nanotechnol. 2016 May;16(5):5058-62. PubMed PMID: 27483871. 19: Wang X, Yang Y, Chen N, Liu B, Liu G. Preparation of LaF3:Eu3+ Based Inorganic-Organic Hybrid Nanostructures via an Ion Exchange Method and Their Strong Luminescence. J Nanosci Nanotechnol. 2016 Apr;16(4):3729-34. PubMed PMID: 27451698. 20: Li B, Li H, Chen P, Sun W, Wang C, Gao T, Yan P. Insight into the roles of structures and energy levels of mono- and bis-β-diketones on sensitizing Nd(iii) NIR-luminescence. Dalton Trans. 2016 Jul 28;45(28):11459-70. doi: 10.1039/c6dt01609j. Epub 2016 Jun 27. PubMed PMID: 27346610.