HR-546 | CAS# 62151-21-7 | Biochemical

MedKoo Cat#: 576374 | Name: HR-546

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.

Chemical Structure

HR-546

CAS#62151-21-7

Theoretical Analysis

MedKoo Cat#: 576374

Name: HR-546

CAS#: 62151-21-7

Chemical Formula: C26H44O6

Exact Mass: 452.3138

Molecular Weight: 452.63

Elemental Analysis: C, 68.99; H, 9.80; O, 21.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HR 546; HR546; HR-546

IUPAC/Chemical Name

(13E,15S)-1-Ethoxy-15-hydroxy-5-methyl-1,9-dioxoprost-13-ene-8-carboxylic acid, ethyl ester

InChi Key

NNOAMVFGASMLSC-UOKZJOJUSA-N

InChi Code

InChI=1S/C26H44O6/c1-5-8-9-12-22(27)16-14-21-15-17-23(28)26(21,25(30)32-7-3)19-18-20(4)11-10-13-24(29)31-6-2/h14,16,20-22,27H,5-13,15,17-19H2,1-4H3/b16-14+/t20?,21-,22-,26-/m0/s1

SMILES Code

CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)[C@@]1(CCC(C)CCCC(=O)OCC)C(=O)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 452.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Adaikan PG, Karim SM. Non-specific prostaglandin antagonism by 8-ethoxycarbonyl-5-methyl-10, 11-dihydro-PGA1-ethyl ester (HR 546) on some smooth muscle preparations in vitro. Prostaglandins. 1977 Oct;14(4):653-7. doi: 10.1016/0090-6980(77)90192-7. PMID: 594369. 2. Wienbeck M, Sperling T. The effects of prostaglandins F2 alpha and E2 on the motility of the cat colon in vitro. Z Gastroenterol. 1984 Oct;22(10):580-5. PMID: 6594832.