Synonym
Bendazol HCl; Bendazol hydrochloride; Dibazolum
IUPAC/Chemical Name
2-Benzyl-1H-benzimidazole monohydrochloride
InChi Key
CJTQARUHALKPGG-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H12N2.ClH/c1-2-6-11(7-3-1)10-14-15-12-8-4-5-9-13(12)16-14;/h1-9H,10H2,(H,15,16);1H
SMILES Code
[H]Cl.C1(CC2=CC=CC=C2)=NC3=CC=CC=C3N1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
244.72
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Tong L, Cui D, Zeng J. Topical bendazol inhibits experimental myopia progression and decreases the ocular accumulation of HIF-1α protein in young rabbits. Ophthalmic Physiol Opt. 2020 Sep;40(5):567-576. doi: 10.1111/opo.12717. Epub 2020 Aug 24. PMID: 32839973.
2: Khan W, Khan J, Rahman A, Ullah H, Salim M, Iqbal M, Khan I, Salman M, Munir B. Albendazole in the treatment of Hymenolepiasis in school children. Pak J Pharm Sci. 2018 Jan;31(1(Suppl.)):305-309. PMID: 29386158.
3: Kuzubova EA, Spasov AA, Bugaeva LI, Bukatin MV. [Effect of dibazol (bendazol) on the generative function in rats]. Eksp Klin Farmakol. 2007 Mar- Apr;70(2):37-9. Russian. PMID: 17523449.
4: Eliseeva EV, Romanchenko EF, Dyuizen IV, Tyrtyshnikova AV, Pigolkin YI. Effect of Hypotensive Drugs on Dynamics of Nitroxide-Producing Renal Function in Rats with Nephrogenic Hypertension. Bull Exp Biol Med. 2017 Jan;162(3):357-361. doi: 10.1007/s10517-017-3615-3. Epub 2017 Jan 14. PMID: 28091926.
5: Huo Z, Chen L. Base-deactivated and alkaline-resistant chromatographic stationary phase based on functionalized polymethylsilsesquioxane microspheres. J Sep Sci. 2020 Jan;43(2):389-397. doi: 10.1002/jssc.201900634. Epub 2019 Nov 6. PMID: 31631562.
6: Sorokina SS, Zaichkina SI, Rozanova OM, Aptikaeva GF, Akhmadieva AKh, Smirnova EN, Romanchenko SP, Vakhrusheva OA, Dyukina AR, Peleshko VN. Delayed effects of chronic low-dose high linear energy transfer (LET) radiation on mice in vivo. Radiat Prot Dosimetry. 2011 Feb;143(2-4):305-10. doi: 10.1093/rpd/ncq531. Epub 2010 Dec 24. PMID: 21186211.
7: Chan Del Pino M, Cueva Cornejo L, Troyes Rivera L. Comparación de Albendazol con nitrofuranos y nitroimidazoles en el tratamiento de giardiasis en ni os [COMPARATIVE STUDY OF ALBENDAZOLE VERSUS NITROFURANS AND NITROIMIDAZOLES IN THE TREATMENT OF GIARDIASIS IN CHILDREN]. Rev Gastroenterol Peru. 1999 Apr- Jun;19(2):95-108. Spanish. PMID: 12196811.
8: Zarivchatskiĭ MF. Primenenie gel'visola dlia predoperatsionnoĭ podgotovki bol'nykh toksicheskim zobom [Use of gelvisol in the preparation of patients with toxic goiter for surgery]. Vestn Khir Im I I Grek. 1983 Dec;131(12):12-4. Russian. PMID: 6689454.
9: Valenkevich LN, Radzevich GI, Orlova ZI, Sukhanova VF, Kozlov OA. O lechebnom deĭstvii gel'visola pri khronicheskom kholetsistite [Therapeutic action of gelvisol in chronic cholecystitis]. Vrach Delo. 1980 Jul;(7):58-60. Russian. PMID: 7415096.
10: Zarivchatskiĭ MF. Osobennosti intraintestinal'nogo vsasyvaniia lechebnogo rastvora gel'visola pri normal'nom krovoobrashchenii, krovopotere i travme [Characteristics of intraintestinal absorption of therapeutic solution of gelvisol in normal blood circulation, blood loss and trauma]. Probl Gematol Pereliv Krovi. 1978 Oct;23(10):43-6. Russian. PMID: 714887.
