1: Chopin P, Colpaert FC, Marien M. Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents. J Pharmacol Exp Ther. 2002 Apr;301(1):187-96. doi: 10.1124/jpet.301.1.187. PMID: 11907173.
2: Debeir T, Marien M, Ferrario J, Rizk P, Prigent A, Colpaert F, Raisman-Vozari R. In vivo upregulation of endogenous NGF in the rat brain by the alpha2-adrenoreceptor antagonist dexefaroxan: potential role in the protection of the basalocortical cholinergic system during neurodegeneration. Exp Neurol. 2004 Dec;190(2):384-95. doi: 10.1016/j.expneurol.2004.08.023. PMID: 15530877.
3: Rizk P, Salazar J, Raisman-Vozari R, Marien M, Ruberg M, Colpaert F, Debeir T. The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells. Neuropsychopharmacology. 2006 Jun;31(6):1146-57. doi: 10.1038/sj.npp.1300954. PMID: 16292321.
4: Debeir T, Marien M, Chopin P, Martel JC, Colpaert F, Raisman-Vozari R. Protective effects of the alpha 2-adrenoceptor antagonist, dexefaroxan, against degeneration of the basalocortical cholinergic system induced by cortical devascularization in the adult rat. Neuroscience. 2002;115(1):41-53. doi: 10.1016/s0306-4522(02)00406-2. PMID: 12401320.
5: Bauer S, Moyse E, Jourdan F, Colpaert F, Martel JC, Marien M. Effects of the alpha 2-adrenoreceptor antagonist dexefaroxan on neurogenesis in the olfactory bulb of the adult rat in vivo: selective protection against neuronal death. Neuroscience. 2003;117(2):281-91. doi: 10.1016/s0306-4522(02)00757-1. PMID: 12614670.
6: Chopin P, Debeir T, Raisman-Vozari R, Colpaert FC, Marien MR. Protective effect of the alpha2-adrenoceptor antagonist, dexefaroxan, against spatial memory deficit induced by cortical devascularization in the adult rat. Exp Neurol. 2004 Jan;185(1):198-200. doi: 10.1016/j.expneurol.2003.09.010. PMID: 14697331.
7: Villégier AS, Drouin C, Bizot JC, Marien M, Glowinski J, Colpaërt F, Tassin JP. Stimulation of postsynaptic alpha1b- and alpha2-adrenergic receptors amplifies dopamine-mediated locomotor activity in both rats and mice. Synapse. 2003 Dec 15;50(4):277-84. doi: 10.1002/syn.10267. PMID: 14556232.
8: Estrade L, Cassel JC, Parrot S, Duchamp-Viret P, Ferry B. Microdialysis Unveils the Role of the α2-Adrenergic System in the Basolateral Amygdala during Acquisition of Conditioned Odor Aversion in the Rat. ACS Chem Neurosci. 2019 Apr 17;10(4):1929-1934. doi: 10.1021/acschemneuro.8b00314. Epub 2018 Sep 10. PMID: 30179513.
9: Francis BM, Yang J, Hajderi E, Brown ME, Michalski B, McLaurin J, Fahnestock M, Mount HT. Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease. Neuropsychopharmacology. 2012 Jul;37(8):1934-44. doi: 10.1038/npp.2012.40. Epub 2012 Apr 11. PMID: 22491352; PMCID: PMC3376325.
10: Pauwels PJ, Colpaert FC. Disparate ligand-mediated Ca(2+) responses by wild- type, mutant Ser(200)Ala and Ser(204)Ala alpha(2A)-adrenoceptor: G(alpha15) fusion proteins: evidence for multiple ligand-activation binding sites. Br J Pharmacol. 2000 Aug;130(7):1505-12. doi: 10.1038/sj.bjp.0703455. PMID: 10928951; PMCID: PMC1572214.