HA-7 | CAS# 201943-88-6 | Biochemical

MedKoo Cat#: 576174 | Name: HA-7

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HA-7 is an anti-arrhythmic agent.

Chemical Structure

HA-7

CAS#201943-88-6

Theoretical Analysis

MedKoo Cat#: 576174

Name: HA-7

CAS#: 201943-88-6

Chemical Formula: C19H15NO4

Exact Mass: 321.1001

Molecular Weight: 321.33

Elemental Analysis: C, 71.02; H, 4.71; N, 4.36; O, 19.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

HA-7; HA 7; HA7

IUPAC/Chemical Name

FURO(2,3-b)quinoline-3,4(2H,9H)-dione, 7-methoxy-9-(phenylmethyl)-

InChi Key

GUAIXKMHFDVZEQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H15NO4/c1-23-13-7-8-14-15(9-13)20(10-12-5-3-2-4-6-12)19-17(18(14)22)16(21)11-24-19/h2-9H,10-11H2,1H3

SMILES Code

COc1ccc2C(=O)C3=C(OCC3=O)N(Cc4ccccc4)c2c1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

to be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	To be determined	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 321.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Chang GJ, Su MJ, Kuo SC, Lin TP, Lee YS. Multiple cellular electrophysiological effects of a novel antiarrhythmic furoquinoline derivative HA-7 [N-benzyl-7-methoxy-2,3,4,9-tetrahydrofuro[2,3-b]quinoline-3,4-dione] in guinea pig cardiac preparations. J Pharmacol Exp Ther. 2006 Jan;316(1):380-91. doi: 10.1124/jpet.105.092106. Epub 2005 Sep 20. PMID: 16174797. 2. Su MJ, Chang GJ, Wu MH, Kuo SC. Electrophysiological basis for the antiarrhythmic action and positive inotropy of HA-7, a furoquinoline alkaloid derivative, in rat heart. Br J Pharmacol. 1997 Dec;122(7):1285-98. doi: 10.1038/sj.bjp.0701510. PMID: 9421274; PMCID: PMC1565072.