Zamifenacin fumarate is an antagonist of M3 muscarinic acetylcholine receptors. It is selective for M3 over M1, M2, M4, and M5 receptors in radioligand binding assays using cells expressing recombinant human receptors. Zamifenacin fumarate inhibits cholecystokinin-induced small bowel motility but does not increase heart rate in dogs.
MedKoo Cat#: 463667
Name: Zamifenacin fumarate
CAS#: 127308-98-9 (fumarate)
Chemical Formula: C31H33NO7
Exact Mass: 531.2257
Molecular Weight: 531.61
Elemental Analysis: C, 70.04; H, 6.26; N, 2.63; O, 21.07
The following data is based on the product molecular weight 531.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
