Synonym
Palmitic anhydride; Palmitic acid anhydride; NSC 285112; NSC285112; NSC-285112;
IUPAC/Chemical Name
palmitic anhydride
InChi Key
QWZBEFCPZJWDKC-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H62O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31(33)35-32(34)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-30H2,1-2H3
SMILES Code
CCCCCCCCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Biological target:
Palmitic anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Solvent |
mg/mL |
mM |
| Solubility |
| Soluble in DMSO |
0.0 |
100.00 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
494.85
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Formulation protocol:
TBD
1: Lee S, Shin H, Bae J, Lee T, Kim M, Jeon HB, Lee KH, Yoo HY, Park C. Enhanced Enzymatic Synthesis of Puerarin Palmitate with Different Acyl Donors for Lipid Solubility Improvement. Int J Mol Sci. 2024 Jan 5;25(2):709. doi: 10.3390/ijms25020709. PMID: 38255784; PMCID: PMC10815456.
2: Trabelsi I, Essid K, Frikha MH. Esterification of Mixed Carboxylic-fatty Anhydrides Using Amberlyst-15 as Heterogeneous Catalyst. J Oleo Sci. 2017;66(7):667-676. doi: 10.5650/jos.ess17008. PMID: 28674327.
3: de la Iglesia P, Fonollosa E, Diogène J. Assessment of acylation routes and structural characterisation by liquid chromatography/tandem mass spectrometry of semi-synthetic acyl ester analogues of lipophilic marine toxins. Rapid Commun Mass Spectrom. 2014 Dec 15;28(23):2605-16. doi: 10.1002/rcm.7057. PMID: 25366407.
4: Aasen JA, Hardstaff W, Aune T, Quilliam MA. Discovery of fatty acid ester metabolites of spirolide toxins in mussels from Norway using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(10):1531-7. doi: 10.1002/rcm.2501. PMID: 16628595.
5: Jiang GB, Quan D, Liao K, Wang H. Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery. Mol Pharm. 2006 Mar-Apr;3(2):152-60. doi: 10.1021/mp050010c. PMID: 16579644.
6: Apte SS, Weber N, Mangold HK. Biologically active ether lipids. Biotransformation of rac-1(3)-O-alkylglycerols in cell suspension cultures of rape and semisynthesis of 1-O-alkyl-2-palmitoyl-sn- glycero-3-phospho-(N-palmitoyl)ethanolamines, potent antitumor agents. FEBS Lett. 1990 Jun 4;265(1-2):104-6. doi: 10.1016/0014-5793(90)80894-o. PMID: 2365047.
7: Donohue TJ, Cain BD, Kaplan S. Purification and characterization of an N-acylphosphatidylserine from Rhodopseudomonas sphaeroides. Biochemistry. 1982 May 25;21(11):2765-73. doi: 10.1021/bi00540a029. PMID: 6980013.
