Synonym
Cyprodenate maleate; EINECS 244-883-2
IUPAC/Chemical Name
(2-(3-Ethoxy-3-oxopropyl)cyclohexyl)dimethylammonium hydrogen maleate
InChi Key
KJDGINDHADLMKF-BTJKTKAUSA-N
InChi Code
InChI=1S/C13H25NO2.C4H4O4/c1-4-16-13(15)10-9-11-7-5-6-8-12(11)14(2)3;5-3(6)1-2-4(7)8/h11-12H,4-10H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES Code
C[NH+](C1C(CCC(OCC)=O)CCCC1)C.O=C(O)/C=C\C([O-])=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
comments |
| Solubility |
| Soluble in DMSO |
0.0 |
100.00 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
343.42
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Dormard Y, Levron JC, Benakis A. Pharmacokinetic study of maleate acid of 2-(N,N-dimethylaminoethanol-14C1)-cyclohexylpropionate (cyprodenate) and of N,N-dimethylaminoethanol-14C1 in animals. Arzneimittelforschung. 1975 Feb;25(2):194-201. PubMed PMID: 1173032.
2: Dormard Y, Levron JC, Le Fur JM. Pharmacokinetic study of maleate acid of 2-(N,N-dimethylaminoethanol-14C1)-cyclohexylpropionate (cyprodenate) and of N,N-dimethylaminoethanol-14C1 in animals. Arzneimittelforschung. 1975 Feb;25(2):201-7. PubMed PMID: 1173033.
3: Bobkov IuG, Morozov IS. [Correction of psychodepressive effects of benzodiazepine tranquilizers by administration of psychostimulants]. Biull Eksp Biol Med. 1982 Oct;94(10):48-51. Russian. PubMed PMID: 6129008.
4: Förster A, Falcone FH, Gibbs BF, Preussner LM, Fiebig BS, Altunok H, Seeger JM, Cerny-Reiterer S, Rabenhorst A, Papenfuss K, Valent P, Kashkar H, Hartmann K. Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils. Leuk Lymphoma. 2013 Apr;54(4):835-42. doi: 10.3109/10428194.2012.731600. Epub 2012 Oct 9. PubMed PMID: 22989017.
5: Bergener M, Freistein H. The use of Wittenborn psychiatric rating scales in geriatric psychiatry. Results of a double blind study with cyprodenate and placebo. Arzneimittelforschung. 1972 Dec;22(12):2058-63. German. PubMed PMID: 4575344.
