LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alone or in Combination With Pembrolizumab is now under trials for patients with Advanced Cancer.
MedKoo Cat#: 207152
Name: LY-3475070
CAS#: 2375815-63-5
Chemical Formula: C15H18N4O2
Exact Mass: 286.1430
Molecular Weight: 286.34
Elemental Analysis: C, 62.92; H, 6.34; N, 19.57; O, 11.18
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 78.5 | 274.15 | |
| Ethanol | 10.0 | 34.92 |
The following data is based on the product molecular weight 286.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
