Guanfacine | CAS# 29110-47-2 | Biochemical

MedKoo Cat#: 576057 | Name: Guanfacine

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Guanfacine is a centrally acting antihypertensive agent with specificity towards adrenergic alpha-2 receptors.

Chemical Structure

Guanfacine

CAS#29110-47-2 (free base)

Theoretical Analysis

MedKoo Cat#: 576057

Name: Guanfacine

CAS#: 29110-47-2 (free base)

Chemical Formula: C9H9Cl2N3O

Exact Mass: 245.0123

Molecular Weight: 246.09

Elemental Analysis: C, 43.93; H, 3.69; Cl, 28.81; N, 17.08; O, 6.50

Price and Availability

Size	Price	Availability
100mg	USD 350.00	2 Weeks
250mg	USD 650.00	2 Weeks
1g	USD 1,450.00	2 Weeks

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Related CAS #

29110-48-3 (HCl) 29110-47-2 (free base)

Synonym

Guanfacine; Guanfacina; Guanfacinum; NSC-759121; NSC759121; NSC 759121

IUPAC/Chemical Name

Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-

InChi Key

INJOMKTZOLKMBF-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)

SMILES Code

NC(=N)NC(=O)Cc1c(Cl)cccc1Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 246.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Huss M, Chen W, Ludolph AG. Guanfacine Extended Release: A New Pharmacological Treatment Option in Europe. Clin Drug Investig. 2016 Jan;36(1):1-25. doi: 10.1007/s40261-015-0336-0. PMID: 26585576; PMCID: PMC4706844.