Synonym
GS 7443; GS-7443; GS7443; Mequidox
IUPAC/Chemical Name
2-Quinoxalinemethanol, 3-methyl-, 1,4-dioxide
InChi Key
MZRHTYDFTZJMLV-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H10N2O3/c1-7-10(6-13)12(15)9-5-3-2-4-8(9)11(7)14/h2-5,13H,6H2,1H3
SMILES Code
Cc1c(CO)n(=O)c2ccccc2n1=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
| Solubility |
| Soluble in DMSO |
0.0 |
100.00 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
206.20
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Liu Q, Lei Z, Gu C, Guo J, Yu H, Fatima Z, Zhou K, Shabbir MAB, Maan MK, Wu Q, Xie S, Wang X, Yuan Z. Mequindox induces apoptosis, DNA damage, and carcinogenicity in Wistar rats. Food Chem Toxicol. 2019 May;127:270-279. doi: 10.1016/j.fct.2019.03.025. Epub 2019 Mar 25. PMID: 30922968.
2. He T, Wang Y, Qian M, Wu C. Mequindox resistance and in vitro efficacy in animal-derived Escherichia coli strains. Vet Microbiol. 2015 Jun 12;177(3-4):341-6. doi: 10.1016/j.vetmic.2015.04.007. Epub 2015 Apr 14. PMID: 25912025.
3. Chen L, Wei J, An M, Zhang L, Lin S, Shu G, Yuan Z, Lin J, Peng G, Liang X, Yin L, Zhang W, Zhao L, Fu H. Casein nanoparticles as oral delivery carriers of mequindox for the improved bioavailability. Colloids Surf B Biointerfaces. 2020 Jun 25;195:111221. doi: 10.1016/j.colsurfb.2020.111221. Epub ahead of print. PMID: 32652401.
