MedKoo Cat#: 413338 | Name: Fenticlor
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fenticlor is a topical Anti-Infective

Chemical Structure

Fenticlor
Fenticlor
CAS#97-24-5

Theoretical Analysis

MedKoo Cat#: 413338

Name: Fenticlor

CAS#: 97-24-5

Chemical Formula: C12H8Cl2O2S

Exact Mass: 285.9622

Molecular Weight: 287.15

Elemental Analysis: C, 50.19; H, 2.81; Cl, 24.69; O, 11.14; S, 11.16

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 650.00 2 Weeks
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Related CAS #
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Synonym
Fenticlor; Fentichlor; NSC 55636; NSC55636; NSC-55636; NSC 4112; NSC4112; NSC-4112
IUPAC/Chemical Name
2,2'-Dihydroxy-5,5'-dichlorodiphenyl sulfide
InChi Key
ANUSOIHIIPAHJV-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H8Cl2O2S/c13-7-1-3-9(15)11(5-7)17-12-6-8(14)2-4-10(12)16/h1-6,15-16H
SMILES Code
ClC1=CC=C(O)C(SC2=CC(Cl)=CC=C2O)=C1
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 287.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hinoshita M, Abe T, Sato A, Maeda Y, Takeyoshi M. False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine. J Toxicol Sci. 2022;47(12):503-506. doi: 10.2131/jts.47.503. PMID: 36450494. 2: Ashurst PJ. Fenticlor combined with triamcinolone acetonide in the treatment of infected dermatoses. Br J Clin Pract. 1972 Sep;26(9):409-12. PMID: 4562672. 3: Burry JN. Photoallergies to fenticlor and Multifungin. Arch Dermatol. 1967 Mar;95(3):287-91. PMID: 6019797. 4: Burry JN. Letter: Fenticlor, actinic reticuloid, and antihistamines. Br Med J. 1974 Jun 8;2(5918):556-7. doi: 10.1136/bmj.2.5918.556-c. PMID: 4152080; PMCID: PMC1610938. 5: Burry JN. Cross sensitivity between fenticlor and bithinol. Arch Dermatol. 1968 May;97(5):497-502. PMID: 5647026. 6: Vigan M, Girardin P, Desprez P, Adessi B, Aubin F, Laurent R. Photoallergie au kétoprofène et photosensibilisations au tétrachlorosalicylanide et au Fenticlor(R) [Photocontact dermatitis due to ketoprofen and photosensitization to tetrachlorosalicylanide and to Fenticlor(R)]. Ann Dermatol Venereol. 2002 Oct;129(10 Pt 1):1125-7. French. PMID: 12442124. 7: Neumann NJ, Hölzle E, Lehmann P, Benedikter S, Tapernoux B, Plewig G. Pattern analysis of photopatch test reactions. Photodermatol Photoimmunol Photomed. 1994 Apr;10(2):65-73. PMID: 8043387. 8: Fogg AG, Gray A, Burns DT. Stability constants of metal complexes of bithionol, fenticlor and hexachlorophene. Anal Chim Acta. 1970 Aug;51(2):265-70. doi: 10.1016/S0003-2670(01)95715-0. PMID: 5448738. 9: Fogg AG, Gray A, Miller JN, Burns DT. The use of acid dissociation constants in selecting buffers to effect the electrophoretic separation of bithionol, fenticlor, hexachlorophene, bromchlorophene, dichlorophene, tetrachlorophene and 4-hexylresorcinol. J Chromatogr. 1970 Jun 24;49(3):567-72. doi: 10.1016/s0021-9673(00)93681-1. PMID: 5430417. 10: Foti C, Bonamonte D, Conserva A, Stingeni L, Lisi P, Lionetti N, Rigano L, Angelini G. Allergic and photoallergic contact dermatitis from ketoprofen: evaluation of cross-reactivities by a combination of photopatch testing and computerized conformational analysis. Curr Pharm Des. 2008;14(27):2833-9. doi: 10.2174/138161208786369696. PMID: 18991702. 11: Schmeltzer RC, Uhrich KE. Synthesis and characterization of antiseptic-based poly(anhydride-esters). Polym Bull (Berl). 2006 Jul 1;57(3):281-291. doi: 10.1007/s00289-006-0561-z. PMID: 24039323; PMCID: PMC3769797. 12: Hinoshita M, Abe T, Sato A, Maeda Y, Takeyoshi M. Modified ESR-based photosafety test (ESR-PT) detecting singlet oxygen and free radical formation. J Appl Toxicol. 2023 Dec 6. doi: 10.1002/jat.4569. Epub ahead of print. PMID: 38058230. 13: de la Cuadra-Oyanguren J, Pérez-Ferriols A, Lecha-Carrelero M, Giménez-Arnau AM, Fernández-Redondo V, Ortiz de Frutos FJ, Silvestre-Salvador JF, Serra- Baldrich E. Resultados y evaluación del fotoparche en España: hacia una nueva batería estándar de fotoalergenos [Results and assessment of photopatch testing in Spain: towards a new standard set of photoallergens]. Actas Dermosifiliogr. 2007 Mar;98(2):96-101. Spanish. PMID: 17397595. 14: Pevny I. Pestizid-Allergie Allergisches Kontaktekzem bei einer Winzerin [Pesticide allergy - allergic contact eczema of a vintner (author's transl)]. Derm Beruf Umwelt. 1980;28(6):186-9. German. PMID: 7460769. 15: Gritiyarangsan P. A three-year photopatch study in Thailand. J Dermatol Sci. 1991 Sep;2(5):371-5. doi: 10.1016/0923-1811(91)90031-r. PMID: 1742247. 16: Jeanmougin M, Manciet JR, Dubertret L. Photoallergie de contact au fenticlor présent dans und savon d'hygiène pour les mains [Contact fentichlor photoallergy from soap for handwashing]. Ann Dermatol Venereol. 1992;119(12):983-5. French. PMID: 1304693.