HSP27-IN-I is a novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC50 values around 5 nM.
MedKoo Cat#: 464045
Name: HSP27-IN-I
CAS#: unknown
Chemical Formula: C25H28N2O7S
Exact Mass: 500.1617
Molecular Weight: 500.57
Elemental Analysis: C, 59.99; H, 5.64; N, 5.60; O, 22.37; S, 6.40
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 500.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |