Hortein is a synthetic small-molecule inhibitor designed to selectively target and modulate histone deacetylase (HDAC) activity, particularly within Class I isoforms. By interfering with HDAC-mediated chromatin remodeling, Hortein promotes transcriptional activation of tumor suppressor genes and can induce cell cycle arrest in cancer models. Its high bioavailability and target specificity make it a promising tool for epigenetic research and preclinical oncology studies.
MedKoo Cat#: 464008
Name: Hortein
CAS#: 346610-88-6
Chemical Formula: C20H12O6
Exact Mass: 348.0634
Molecular Weight: 348.31
Elemental Analysis: C, 68.97; H, 3.47; O, 27.56
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 348.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
