Closiramine is an antihistamine drug developed by Schering in the 1970s. The drug was evaluated in phase 1 clinical trial on healthy volunteers. The results show that in a therapeutic dose of 2 mg the drug did not have any effects which might lead to an impairment of driving ability.
MedKoo Cat#: 413185
Name: Closiramine
CAS#: 47135-88-6 (free base)
Chemical Formula: C18H21ClN2
Exact Mass: 300.1393
Molecular Weight: 300.83
Elemental Analysis: C, 71.87; H, 7.04; Cl, 11.78; N, 9.31
The following data is based on the product molecular weight 300.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
