MedKoo Cat#: 463948 | Name: Methyldopa anhydrous
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.

Chemical Structure

Methyldopa anhydrous
Methyldopa anhydrous
CAS#55-40-3

Theoretical Analysis

MedKoo Cat#: 463948

Name: Methyldopa anhydrous

CAS#: 55-40-3

Chemical Formula: C10H13NO4

Exact Mass: 211.0845

Molecular Weight: 211.22

Elemental Analysis: C, 56.87; H, 6.20; N, 6.63; O, 30.30

Price and Availability

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1g USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
Methyldopa anhydrous; Methyldopa anhydrous, (+/-)-;
IUPAC/Chemical Name
2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
InChi Key
CJCSPKMFHVPWAR-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)
SMILES Code
CC(Cc1cc(O)c(O)cc1)(C(O)=O)N
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 211.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Siahi MR, Rahimi S, Monajjemzadeh F. Analytical Investigation of the Possible Chemical Interaction of Methyldopa with Some Reducing Carbohydrates Used as Pharmaceutical Excipients. Adv Pharm Bull. 2018 Nov;8(4):657-666. doi: 10.15171/apb.2018.074. Epub 2018 Nov 29. PMID: 30607338; PMCID: PMC6311631. 2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Methyldopa. 2018 Oct 31. PMID: 30000085. 3. Burckhardt-Herold S, Klotz J, Funk F, Büchi R, Petrig-Schaffland J, Geisser P. Interactions between iron(III)-hydroxide polymaltose complex and commonly used drugs / simulations and in vitro studies. Arzneimittelforschung. 2007;57(6A):360-9. doi: 10.1055/s-0031-1296684. PMID: 17691585. 4. de Jong AP, Kok RM, Cramers CA, Wadman SK, Haan E. A new method for the determination of L-dopa and 3-O-methyldopa in plasma and cerebrospinal fluid using gas chromatography and electron capture negative ion mass spectrometry. Clin Chim Acta. 1988 Jan 15;171(1):49-61. doi: 10.1016/0009-8981(88)90290-2. PMID: 3127089.