Aranose | CAS# 167396-23-8 | Antineoplastic

MedKoo Cat#: 573263 | Name: Aranose

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aranose is an antineoplastic shown to be effective against experimental lung cancer when combined with cisplatin and gemcitabine. It has also shown anti-tumor activity against melanoma.

Chemical Structure

Aranose

CAS#167396-23-8

Theoretical Analysis

MedKoo Cat#: 573263

Name: Aranose

CAS#: 167396-23-8

Chemical Formula: C7H13N3O6

Exact Mass: 235.0804

Molecular Weight: 235.20

Elemental Analysis: C, 35.75; H, 5.57; N, 17.87; O, 40.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Aranose, Aranoza, CRC-0510375

IUPAC/Chemical Name

3-(alpha-L-Arabinopyranosyl)-1-methyl-1-nitrosourea

InChi Key

BADMGRJDJPQBLS-UNTFVMJOSA-N

InChi Code

1S/C7H13N3O6/c1-10(9-15)7(14)8-6-5(13)4(12)3(11)2-16-6/h3-6,11-13H,2H2,1H3,(H,8,14)/t3-,4-,5+,6+/m0/s1

SMILES Code

N([C@@H]1OC[C@H](O)[C@@H](O)[C@H]1O)C(=O)N(C)N=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 235.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pokrovsky VS, Lesnaya NA, Romanenko VI, Treshalina EM. Efficiency and tolerance of aranose combinations with cisplatin and gemcitabine in experimental lung cancer. Bull Exp Biol Med. 2009 Dec;148(6):911-4. PubMed PMID: 21116505. 2: Pokrovskiĭ VS, Treshchalin MI, Bodiagin DA, Treshchalina EM. [Hematological toxicity of some combined chemotherapy schemes involving aranoza]. Eksp Klin Farmakol. 2010 May;73(5):36-40. Russian. PubMed PMID: 20597370. 3: Gershanovich ML, Akimov MA. [Chemoimmunotherapy with dacarbazine and aranose combined with interferon-alpha in disseminated cutaneous melanoma]. Vopr Onkol. 2004;50(2):179-83. Russian. PubMed PMID: 15176220. 4: Bayés M, Rabasseda X, Prous JR. Gateways to clinical trials. March 2003. Methods Find Exp Clin Pharmacol. 2003 Mar;25(2):145-68. PubMed PMID: 12731460.