MedKoo Cat#: 575982 | Name: ICI-199441

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-199441 is an antinociceptive.

Chemical Structure

ICI-199441
ICI-199441
CAS#116508-24-8 (free base)

Theoretical Analysis

MedKoo Cat#: 575982

Name: ICI-199441

CAS#: 116508-24-8 (free base)

Chemical Formula: C21H24Cl2N2O

Exact Mass: 390.1266

Molecular Weight: 391.34

Elemental Analysis: C, 64.45; H, 6.18; Cl, 18.12; N, 7.16; O, 4.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
116508-24-8 (free base) 115199-84-3 (HCl) 136328-89-7 (R-isomer) 159531-32-5 (racemic)
Synonym
GR-199,441; GR-199441; GR199441; GR 199441; ICI-199441; ICI 199441; ICI199441
IUPAC/Chemical Name
Benzeneacetamide, 3,4-dichloro-N-methyl-N-((1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl)-
InChi Key
AEJOEPSMZCEYJN-HXUWFJFHSA-N
InChi Code
1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3/t20-/m1/s1
SMILES Code
CN([C@H](CN1CCCC1)c2ccccc2)C(=O)Cc3ccc(Cl)c(Cl)c3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 391.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Endoh T, Tajima A, Suzuki T, Kamei J, Narita M, Tseng L, Nagase H. Characterization of the antinociceptive effects of TRK-820 in the rat. Eur J Pharmacol. 2000 Jan 10;387(2):133-40. doi: 10.1016/s0014-2999(99)00815-8. PMID: 10650153.