Saprisartan potassium | CAS# 146613-90-3 | Biochemical

MedKoo Cat#: 575974 | Name: Saprisartan potassium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.

Chemical Structure

Saprisartan potassium

CAS#146613-90-3 (potassium)

Theoretical Analysis

MedKoo Cat#: 575974

Name: Saprisartan potassium

CAS#: 146613-90-3 (potassium)

Chemical Formula: C25H21BrF3KN4O4S

Exact Mass: 648.0056

Molecular Weight: 649.52

Elemental Analysis: C, 46.23; H, 3.26; Br, 12.30; F, 8.77; K, 6.02; N, 8.63; O, 9.85; S, 4.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

146613-90-3 (potassium) 146623-69-0 (free)

Synonym

GR 138950C; GR138950C; GR-138950C; Saprisartan potassium

IUPAC/Chemical Name

1H-Imidazole-5-carboxamide, 1-((3-bromo-2-(2-(((trifluoromethyl)sulfonyl)amino)phenyl)-5-benzofuranyl)methyl)-4-cyclopropyl-2-ethyl-, monopotassium salt

InChi Key

IASZJGRIPLTJMA-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H21BrF3N4O4S.K/c1-2-19-31-21(14-8-9-14)22(24(30)34)33(19)12-13-7-10-18-16(11-13)20(26)23(37-18)15-5-3-4-6-17(15)32-38(35,36)25(27,28)29;/h3-7,10-11,14H,2,8-9,12H2,1H3,(H2,30,34);/q-1;+1

SMILES Code

[K+].CCc1nc(C2CC2)c(C(=O)N)n1Cc3ccc4oc(c(Br)c4c3)c5ccccc5[N-]S(=O)(=O)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 649.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Charlton ST, Davis SS, Illum L. Evaluation of effect of ephedrine on the transport of drugs from the nasal cavity to the systemic circulation and the central nervous system. J Drug Target. 2007 Jun;15(5):370-7. doi: 10.1080/10611860701393370. PMID: 17541846. 2. Forhead AJ, Jellyman JK, Gillham K, Ward JW, Blache D, Fowden AL. Renal growth retardation following angiotensin II type 1 (AT₁) receptor antagonism is associated with increased AT₂ receptor protein in fetal sheep. J Endocrinol. 2011 Feb;208(2):137-45. doi: 10.1677/JOE-10-0360. Epub 2010 Nov 22. PMID: 21097994.