GR-36246 | CAS# 132461-41-7 | Biochemical

MedKoo Cat#: 575971 | Name: GR-36246

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GR-36246 is a Thromboxane A2-receptor blocker.

Chemical Structure

GR-36246

CAS#132461-41-7

Theoretical Analysis

MedKoo Cat#: 575971

Name: GR-36246

CAS#: 132461-41-7

Chemical Formula: C29H37NO3

Exact Mass: 447.2773

Molecular Weight: 447.62

Elemental Analysis: C, 77.82; H, 8.33; N, 3.13; O, 10.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

GR 36246; GR36246; GR-36246

IUPAC/Chemical Name

4-Hexenoic acid, 6-(2-((1,1'-biphenyl)-4-ylmethoxy)-5-(1-piperidinyl)cyclopentyl)-, (1R-(1alpha(Z),2alpha,5beta))-

InChi Key

OIRAMMLFTXVNIT-ZOFIRBRHSA-N

InChi Code

InChI=1S/C29H37NO3/c31-29(32)13-7-2-6-12-26-27(30-20-8-3-9-21-30)18-19-28(26)33-22-23-14-16-25(17-15-23)24-10-4-1-5-11-24/h1-2,4-6,10-11,14-17,26-28H,3,7-9,12-13,18-22H2,(H,31,32)/b6-2-/t26-,27-,28-/m1/s1

SMILES Code

OC(=O)CC\C=C/C[C@H]1[C@@H](CC[C@H]1N2CCCCC2)OCc3ccc(cc3)c4ccccc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 447.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Sutherland MF, Parkinson MM, Hallett P. Teratogenicity of three substituted 4-biphenyls in the rat as a result of the chemical breakdown and possible metabolism of a thromboxane A2-receptor blocker. Teratology. 1989 Jun;39(6):537-45. doi: 10.1002/tera.1420390604. PMID: 2528217.