GPA-1734 bromide | CAS# 21852-25-5 | Biochemical

MedKoo Cat#: 575953 | Name: GPA-1734 bromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GPA-1734 bromide is an inhibitor of basement membrane collagen synthesis and angiogenesis.

Chemical Structure

GPA-1734 bromide

CAS#21852-25-5 (bromide)

Theoretical Analysis

MedKoo Cat#: 575953

Name: GPA-1734 bromide

CAS#: 21852-25-5 (bromide)

Chemical Formula: C14H12BrNO2

Exact Mass: 305.0051

Molecular Weight: 306.16

Elemental Analysis: C, 54.92; H, 3.95; Br, 26.10; N, 4.58; O, 10.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

757124-42-8 (cation) 21852-25-5 (bromide)

Synonym

GPA1734 bromide; GPA 1734 bromide; GPA-1734 bromide

IUPAC/Chemical Name

8,9-Dihydroxy-7-methylbenzo(b)quinolizinium, bromide

InChi Key

DWNIXHARVTYMBF-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H11NO2.BrH/c1-9-12-8-15-5-3-2-4-11(15)6-10(12)7-13(16)14(9)17;/h2-8,17H,1H3;1H

SMILES Code

[Br-].Cc1c(O)c(O)cc2cc3cccc[n+]3cc12

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Haralabopoulos GC, Grant DS, Kleinman HK, Lelkes PI, Papaioannou SP, Maragoudakis ME. Inhibitors of basement membrane collagen synthesis prevent endothelial cell alignment in matrigel in vitro and angiogenesis in vivo. Lab Invest. 1994 Oct;71(4):575-82. PMID: 7526036. 2. Maragoudakis ME, Missirlis E, Karakiulakis GD, Sarmonica M, Bastakis M, Tsopanoglou N. Basement membrane biosynthesis as a target for developing inhibitors of angiogenesis with anti-tumor properties. Kidney Int. 1993 Jan;43(1):147-50. doi: 10.1038/ki.1993.24. PMID: 7679456.