MedKoo Cat#: 575951 | Name: GP-1-668

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GP-1-668 is an acadesine derivative that acts as a cardioprotective agent and increases the rate and extent of early postischemic recovery. GP-1-668 is the soluble monophosphate of GP-1-343.

Chemical Structure

GP-1-668
GP-1-668
CAS#1039100-00-9

Theoretical Analysis

MedKoo Cat#: 575951

Name: GP-1-668

CAS#: 1039100-00-9

Chemical Formula: C16H20N5O10P

Exact Mass: 473.0948

Molecular Weight: 473.33

Elemental Analysis: C, 40.60; H, 4.26; N, 14.80; O, 33.80; P, 6.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
GP-1-668; GP 1-668; GP1-668
IUPAC/Chemical Name
5-Amino-N-((4-nitrophenyl)methyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
InChi Key
OUEBBIUZRQCBPH-XNIJJKJLSA-N
InChi Code
InChI=1S/C16H20N5O10P/c17-14-11(15(24)18-5-8-1-3-9(4-2-8)21(25)26)19-7-20(14)16-13(23)12(22)10(31-16)6-30-32(27,28)29/h1-4,7,10,12-13,16,22-23H,5-6,17H2,(H,18,24)(H2,27,28,29)/t10-,12-,13-,16-/m1/s1
SMILES Code
Nc1c(ncn1[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)C(=O)NCc3ccc(cc3)[N+](=O)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 473.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Galiñanes M, Zhai X, Bullough D, Mullane KM, Hearse DJ. Protection against injury during ischemia and reperfusion by acadesine derivatives GP-1-468 and GP-1-668. Studies in the transplanted rat heart. J Thorac Cardiovasc Surg. 1995 Sep;110(3):752-61. doi: 10.1016/S0022-5223(95)70108-7. PMID: 7564443.