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MedKoo Cat#: 413104 | Name: Chlordantoin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlordantoin is an antifungal

Chemical Structure

Chlordantoin
Chlordantoin
CAS#5588-20-5

Theoretical Analysis

MedKoo Cat#: 413104

Name: Chlordantoin

CAS#: 5588-20-5

Chemical Formula: C11H17Cl3N2O2S

Exact Mass: 346.0076

Molecular Weight: 347.68

Elemental Analysis: C, 38.00; H, 4.93; Cl, 30.59; N, 8.06; O, 9.20; S, 9.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Chlordantoin; BRN0812596; BRN-0812596; BRN 0812596
IUPAC/Chemical Name
2,4-Imidazolidinedione, 5-(1-ethylpentyl)-3-((trichloromethyl)thio)-
InChi Key
VOGJJBHRUDVEFM-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H17Cl3N2O2S/c1-3-5-6-7(4-2)8-9(17)16(10(18)15-8)19-11(12,13)14/h7-8H,3-6H2,1-2H3,(H,15,18)
SMILES Code
O=C1N(SC(Cl)(Cl)Cl)C(C(C(CC)CCCC)N1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 347.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Morris DF, Sugrue DL. Miconazole nitrate compared with chlordantoin in the treatment of vaginal candidiasis. Br J Vener Dis. 1975 Apr;51(2):123-4. doi: 10.1136/sti.51.2.123. PMID: 1093633; PMCID: PMC1045127. 2: Helander I, Hollmén A, Hopsu-Havu VK. Allergic contact dermatitis to chlordantoin. Contact Dermatitis. 1979 Jan;5(1):54-5. doi: 10.1111/j.1600-0536.1979.tb05539.x. PMID: 421461. 3: Epstein E. Allergic dermatitis from chlordantoin vaginal cream. Report of 2 cases. Obstet Gynecol. 1966 Mar;27(3):369-70. PMID: 5909556. 4: Patrizi G, Sarnella A, Manna A. La clordantoina nella terapia delle affezioni vaginali da Candida albicans [Chlordantoin in the therapy of vaginal diseases caused by Candida albicans]. Quad Clin Ostet Ginecol. 1966 Nov;21(11):817-22. Italian. PMID: 5999222. 5: Maher M, Ao H, Banke T, Nasser N, Wu NT, Breitenbucher JG, Chaplan SR, Wickenden AD. Activation of TRPA1 by farnesyl thiosalicylic acid. Mol Pharmacol. 2008 Apr;73(4):1225-34. doi: 10.1124/mol.107.042663. Epub 2008 Jan 2. PMID: 18171730. 6: Lemire S. Vaginite à Candida albicans: aspects cliniques et traitement par le chlordantoin [Candida albicans vaginitis: clinical aspects and chlordantoin therapy]. Can Med Assoc J. 1968 Aug 3;99(5):211-3. PMID: 5671127; PMCID: PMC1924362. 7: USHIJIMA Y. [EXPERIENCE IN THE USE OF CHLORDANTOIN, A NEW DRUG FOR THE TREATMENT OF LEUKORRHEA]. Fukuoka Igaku Zasshi. 1963 Dec;54:1302-5. Japanese. PMID: 14118806. 8: O'BRIEN JR. CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS. Can Med Assoc J. 1964 May 23;90(21):1206-12. PMID: 14144540; PMCID: PMC1927158. 9: GARRARD HF. The treatment of cutaneous monilliasis with chlordantoin. Med Times. 1962 Nov;90:1243-9. PMID: 13946624. 10: KAMINSKY A, MOSOVICH F, DE KAMINSKY AR. [Therapeutic trail: chlordantoin in the treatment of moniliasic vulvovaginitis]. Rev Asoc Med Argent. 1961 Aug;75:444-6. Spanish. PMID: 14453474.