Synonym
GLG-V 13; Glg-V-13
IUPAC/Chemical Name
(4-(1H-imidazol-1-yl)phenyl)(7-isopropyl-3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone perchlorate
InChi Key
QCWQRWSUDHQWEI-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26N4O.ClHO4/c1-15(2)23-10-16-9-17(11-23)13-24(12-16)20(25)18-3-5-19(6-4-18)22-8-7-21-14-22;2-1(3,4)5/h3-8,14-17H,9-13H2,1-2H3;(H,2,3,4,5)
SMILES Code
CC(C)N1CC2CC(C1)CN(C2)C(=O)c3ccc(cc3)n4ccnc4.OCl(=O)(=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
438.91
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Fazekas T, Carlsson L, Scherlag BJ, Mabo P, Poty H, Palmer M, Patterson E, Berlin KD, Garrison GL, Lazzara R. Electrophysiological and inotropic characterization of a novel class III antiarrhythmic agent, GLG-V-13, in the mammalian heart. J Cardiovasc Pharmacol. 1996 Aug;28(2):182-91. doi: 10.1097/00005344-199608000-00002. PMID: 8856472.
2. Chen CL, Chandra SA, Kim S, Sangiah S, Chen H, Roder JD, Qualls CW Jr, Garrison GL, Cowell RL, Berlin KD, Scherlag BJ, Lazzara R. Preliminary acute and subchronic toxicity studies of GLG-V-13, a novel class III antiarrhythmic agent, in mice. Arzneimittelforschung. 2000 Jan;50(1):31-8. doi: 10.1055/s-0031-1300160. PMID: 10683713.