GLA-27 | CAS# 89756-57-0 | Biochemical

MedKoo Cat#: 575883 | Name: GLA-27

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GLA-27 is an antiviral and immunomodulator.

Chemical Structure

GLA-27

CAS#89756-57-0

Theoretical Analysis

MedKoo Cat#: 575883

Name: GLA-27

CAS#: 89756-57-0

Chemical Formula: C48H92NO12P

Exact Mass: 905.6357

Molecular Weight: 906.23

Elemental Analysis: C, 63.62; H, 10.23; N, 1.55; O, 21.19; P, 3.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

GLA-27; GLA 27; GLA27

IUPAC/Chemical Name

D-Glucose, 2-deoxy-2-((1-oxo-3-((1-oxotetradecyl)oxy)tetradecyl)amino)-, 4-(dihydrogen phosphate) 3-tetradecanoate

InChi Key

SOZNVTRORYUXFD-NPIQVXMPSA-N

InChi Code

InChI=1S/C48H92NO12P/c1-4-7-10-13-16-19-21-24-27-30-33-36-45(54)59-41(35-32-29-26-23-18-15-12-9-6-3)38-44(53)49-42(39-50)47(48(43(52)40-51)61-62(56,57)58)60-46(55)37-34-31-28-25-22-20-17-14-11-8-5-2/h39,41-43,47-48,51-52H,4-38,40H2,1-3H3,(H,49,53)(H2,56,57,58)/t41?,42-,43+,47+,48+/m0/s1

SMILES Code

CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)N[C@@H](C=O)[C@@H](OC(=O)CCCCCCCCCCCCC)[C@H](OP(=O)(O)O)[C@H](O)CO

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 906.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Ikeda S, Nishimura C, Nakatsuka M, Homma JY, Kiso M, Hasegawa A. Antiviral and immunomodulating activities of chemically synthesized lipid A-subunit analogues GLA-27 and GLA-60. Antiviral Res. 1988 Jan-Feb;9(1-2):37-46. doi: 10.1016/0166-3542(88)90065-4. PMID: 3389769. 2. Ikeda S, Kumazawa Y, Sai K, Nishimura C, Nakatsuka M, Homma JY, Yamamoto A, Kiso M, Hasegawa A. Immunopharmacological activities of chemically synthesized lipid A-subunit analogue GLA-27 combined with muramyl dipeptide via spacers of different carbon chain length. Int J Immunopharmacol. 1988;10(4):339-46. doi: 10.1016/0192-0561(88)90119-1. PMID: 2459075.